A multicellular view of cytokinesis in epithelial tissue

Highlights • Cytokinesis in epithelial tissues needs to counteract the tension imposed by surrounding epithelial cells. • Cytokinetic ring constriction is sensed by neighboring cells and acts as a mechanical signal to remodel AJs. • Apical midbody formation on asymmetric or symmetric furrowing regul...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Trends in cell biology 2014-05, Vol.24 (5), p.285-293
Hauptverfasser:	Herszterg, Sophie, Pinheiro, Diana, Bellaïche, Yohanns
Format:	Artikel
Sprache:	eng
Schlagworte:	actin Actins - metabolism adherens junction Adherens Junctions - metabolism Animals Cadherins Cell Polarity Cytokinesis E-Cadherin Epithelial Cells - physiology epithelial polarity Epithelium - physiology Humans Mechanotransduction, Cellular Myosin II Myosin Type II - metabolism Pathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • Cytokinesis in epithelial tissues needs to counteract the tension imposed by surrounding epithelial cells. • Cytokinetic ring constriction is sensed by neighboring cells and acts as a mechanical signal to remodel AJs. • Apical midbody formation on asymmetric or symmetric furrowing regulates the planar and apical–basal organization of epithelia. • Cytokinesis in epithelia is a multicellular process.
ISSN:	0962-8924 1879-3088
DOI:	10.1016/j.tcb.2013.11.009