The clinical value of cardiac sympathetic imaging in heart failure
Summary The autonomic nervous system plays an important role in the pathology of heart failure. The single‐photon emission computed tomography tracer iodine‐123‐metaiodobenzylguanidine (123I‐MIBG) can be used to investigate the activity of the predominant neurotransmitter of the sympathetic nervous...
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| Veröffentlicht in: | Clinical physiology and functional imaging 2014-05, Vol.34 (3), p.178-182 |
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| container_title | Clinical physiology and functional imaging |
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| creator | Christensen, Thomas Emil Kjaer, Andreas Hasbak, Philip |
| description | Summary
The autonomic nervous system plays an important role in the pathology of heart failure. The single‐photon emission computed tomography tracer iodine‐123‐metaiodobenzylguanidine (123I‐MIBG) can be used to investigate the activity of the predominant neurotransmitter of the sympathetic nervous system, norepinephrine. Also, positron emission tomography tracers are being developed for the same purpose. With 123I‐MIBG as a starting point, this brief review introduces the modalities used for cardiac sympathetic imaging. |
| doi_str_mv | 10.1111/cpf.12091 |
| format | Article |
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The autonomic nervous system plays an important role in the pathology of heart failure. The single‐photon emission computed tomography tracer iodine‐123‐metaiodobenzylguanidine (123I‐MIBG) can be used to investigate the activity of the predominant neurotransmitter of the sympathetic nervous system, norepinephrine. Also, positron emission tomography tracers are being developed for the same purpose. With 123I‐MIBG as a starting point, this brief review introduces the modalities used for cardiac sympathetic imaging.</description><identifier>ISSN: 1475-0961</identifier><identifier>EISSN: 1475-097X</identifier><identifier>DOI: 10.1111/cpf.12091</identifier><identifier>PMID: 24138454</identifier><identifier>CODEN: CPFICA</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>3-Iodobenzylguanidine ; cardiac positron emission tomography ; cardiac single-photon emission computed tomography ; Emission ; Failure ; Heart ; Heart - innervation ; Heart - physiopathology ; Heart failure ; Heart Failure - diagnostic imaging ; Heart Failure - physiopathology ; Humans ; Imaging ; iodine-123-metaiodobenzylguanidine ; Medical imaging ; Norepinephrine ; Pathology ; Positron-Emission Tomography ; Predictive Value of Tests ; Prognosis ; prognostic marker ; Radiopharmaceuticals ; sympathetic nervous system ; Sympathetic Nervous System - diagnostic imaging ; Tomography ; Tomography, Emission-Computed, Single-Photon ; Tracers</subject><ispartof>Clinical physiology and functional imaging, 2014-05, Vol.34 (3), p.178-182</ispartof><rights>2013 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd</rights><rights>2013 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.</rights><rights>Copyright © 2014 Scandinavian Society of Clinical Physiology and Nuclear Medicine</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4901-e162f2300dcea7e023e3f10a2f6ccb38938a8c1224184c72e82b8460e7632743</citedby><cites>FETCH-LOGICAL-c4901-e162f2300dcea7e023e3f10a2f6ccb38938a8c1224184c72e82b8460e7632743</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fcpf.12091$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fcpf.12091$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24138454$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Christensen, Thomas Emil</creatorcontrib><creatorcontrib>Kjaer, Andreas</creatorcontrib><creatorcontrib>Hasbak, Philip</creatorcontrib><title>The clinical value of cardiac sympathetic imaging in heart failure</title><title>Clinical physiology and functional imaging</title><addtitle>Clin Physiol Funct Imaging</addtitle><description>Summary
The autonomic nervous system plays an important role in the pathology of heart failure. The single‐photon emission computed tomography tracer iodine‐123‐metaiodobenzylguanidine (123I‐MIBG) can be used to investigate the activity of the predominant neurotransmitter of the sympathetic nervous system, norepinephrine. Also, positron emission tomography tracers are being developed for the same purpose. With 123I‐MIBG as a starting point, this brief review introduces the modalities used for cardiac sympathetic imaging.</description><subject>3-Iodobenzylguanidine</subject><subject>cardiac positron emission tomography</subject><subject>cardiac single-photon emission computed tomography</subject><subject>Emission</subject><subject>Failure</subject><subject>Heart</subject><subject>Heart - innervation</subject><subject>Heart - physiopathology</subject><subject>Heart failure</subject><subject>Heart Failure - diagnostic imaging</subject><subject>Heart Failure - physiopathology</subject><subject>Humans</subject><subject>Imaging</subject><subject>iodine-123-metaiodobenzylguanidine</subject><subject>Medical imaging</subject><subject>Norepinephrine</subject><subject>Pathology</subject><subject>Positron-Emission Tomography</subject><subject>Predictive Value of Tests</subject><subject>Prognosis</subject><subject>prognostic marker</subject><subject>Radiopharmaceuticals</subject><subject>sympathetic nervous system</subject><subject>Sympathetic Nervous System - diagnostic imaging</subject><subject>Tomography</subject><subject>Tomography, Emission-Computed, Single-Photon</subject><subject>Tracers</subject><issn>1475-0961</issn><issn>1475-097X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqN0UFPFDEUB_DGaATBA1-ANPGih1neazvTmSNuhIUAkrBB46Xpdt-wxdmZtZ1R99tbXNiDCYm9tIff-6fvPcYOEEaYzpFb1SMUUOELtotK5xlU-uvL7bvAHfYmxnsA1FLp12xHKJSlytUu-zhdEHeNb72zDf9pm4F4V3Nnw9xbx-N6ubL9gnrvuF_aO9_ecd_yBdnQ89r6Zgi0z17Vton09vHeY9OTT9PxJLv4fHo2Pr7InKoAM8JC1EICzB1ZTSAkyRrBirpwbibLSpa2dCjS30rltKBSzEpVAOlCCq3kHnu_iV2F7sdAsTdLHx01jW2pG6LBXCIIKFT-HxRFnlelFIm--4fed0NoUx8PCjUoATqpDxvlQhdjoNqsQhpHWBsE87ACk1Zg_q4g2cPHxGG2pPlWPs08gaMN-OUbWj-fZMbXJ0-R2abCx55-byts-G4KLXVuvlydmvPJbQU3-TdzKf8AauCbyg</recordid><startdate>201405</startdate><enddate>201405</enddate><creator>Christensen, Thomas Emil</creator><creator>Kjaer, Andreas</creator><creator>Hasbak, Philip</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TS</scope><scope>7U5</scope><scope>8FD</scope><scope>K9.</scope><scope>L7M</scope><scope>7X8</scope></search><sort><creationdate>201405</creationdate><title>The clinical value of cardiac sympathetic imaging in heart failure</title><author>Christensen, Thomas Emil ; Kjaer, Andreas ; Hasbak, Philip</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4901-e162f2300dcea7e023e3f10a2f6ccb38938a8c1224184c72e82b8460e7632743</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>3-Iodobenzylguanidine</topic><topic>cardiac positron emission tomography</topic><topic>cardiac single-photon emission computed tomography</topic><topic>Emission</topic><topic>Failure</topic><topic>Heart</topic><topic>Heart - innervation</topic><topic>Heart - physiopathology</topic><topic>Heart failure</topic><topic>Heart Failure - diagnostic imaging</topic><topic>Heart Failure - physiopathology</topic><topic>Humans</topic><topic>Imaging</topic><topic>iodine-123-metaiodobenzylguanidine</topic><topic>Medical imaging</topic><topic>Norepinephrine</topic><topic>Pathology</topic><topic>Positron-Emission Tomography</topic><topic>Predictive Value of Tests</topic><topic>Prognosis</topic><topic>prognostic marker</topic><topic>Radiopharmaceuticals</topic><topic>sympathetic nervous system</topic><topic>Sympathetic Nervous System - diagnostic imaging</topic><topic>Tomography</topic><topic>Tomography, Emission-Computed, Single-Photon</topic><topic>Tracers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Christensen, Thomas Emil</creatorcontrib><creatorcontrib>Kjaer, Andreas</creatorcontrib><creatorcontrib>Hasbak, Philip</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Physical Education Index</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical physiology and functional imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Christensen, Thomas Emil</au><au>Kjaer, Andreas</au><au>Hasbak, Philip</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The clinical value of cardiac sympathetic imaging in heart failure</atitle><jtitle>Clinical physiology and functional imaging</jtitle><addtitle>Clin Physiol Funct Imaging</addtitle><date>2014-05</date><risdate>2014</risdate><volume>34</volume><issue>3</issue><spage>178</spage><epage>182</epage><pages>178-182</pages><issn>1475-0961</issn><eissn>1475-097X</eissn><coden>CPFICA</coden><abstract>Summary
The autonomic nervous system plays an important role in the pathology of heart failure. The single‐photon emission computed tomography tracer iodine‐123‐metaiodobenzylguanidine (123I‐MIBG) can be used to investigate the activity of the predominant neurotransmitter of the sympathetic nervous system, norepinephrine. Also, positron emission tomography tracers are being developed for the same purpose. With 123I‐MIBG as a starting point, this brief review introduces the modalities used for cardiac sympathetic imaging.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>24138454</pmid><doi>10.1111/cpf.12091</doi><tpages>5</tpages></addata></record> |
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| ispartof | Clinical physiology and functional imaging, 2014-05, Vol.34 (3), p.178-182 |
| issn | 1475-0961 1475-097X |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | 3-Iodobenzylguanidine cardiac positron emission tomography cardiac single-photon emission computed tomography Emission Failure Heart Heart - innervation Heart - physiopathology Heart failure Heart Failure - diagnostic imaging Heart Failure - physiopathology Humans Imaging iodine-123-metaiodobenzylguanidine Medical imaging Norepinephrine Pathology Positron-Emission Tomography Predictive Value of Tests Prognosis prognostic marker Radiopharmaceuticals sympathetic nervous system Sympathetic Nervous System - diagnostic imaging Tomography Tomography, Emission-Computed, Single-Photon Tracers |
| title | The clinical value of cardiac sympathetic imaging in heart failure |
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