The clinical value of cardiac sympathetic imaging in heart failure

Summary The autonomic nervous system plays an important role in the pathology of heart failure. The single‐photon emission computed tomography tracer iodine‐123‐metaiodobenzylguanidine (123I‐MIBG) can be used to investigate the activity of the predominant neurotransmitter of the sympathetic nervous...

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Veröffentlicht in:	Clinical physiology and functional imaging 2014-05, Vol.34 (3), p.178-182
Hauptverfasser:	Christensen, Thomas Emil, Kjaer, Andreas, Hasbak, Philip
Format:	Artikel
Sprache:	eng
Schlagworte:	3-Iodobenzylguanidine cardiac positron emission tomography cardiac single-photon emission computed tomography Emission Failure Heart Heart - innervation Heart - physiopathology Heart failure Heart Failure - diagnostic imaging Heart Failure - physiopathology Humans Imaging iodine-123-metaiodobenzylguanidine Medical imaging Norepinephrine Pathology Positron-Emission Tomography Predictive Value of Tests Prognosis prognostic marker Radiopharmaceuticals sympathetic nervous system Sympathetic Nervous System - diagnostic imaging Tomography Tomography, Emission-Computed, Single-Photon Tracers
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Zusammenfassung:	Summary The autonomic nervous system plays an important role in the pathology of heart failure. The single‐photon emission computed tomography tracer iodine‐123‐metaiodobenzylguanidine (123I‐MIBG) can be used to investigate the activity of the predominant neurotransmitter of the sympathetic nervous system, norepinephrine. Also, positron emission tomography tracers are being developed for the same purpose. With 123I‐MIBG as a starting point, this brief review introduces the modalities used for cardiac sympathetic imaging.
ISSN:	1475-0961 1475-097X
DOI:	10.1111/cpf.12091