Novel method to analyze post-yield mechanical properties at trabecular bone tissue level

Tissue level mechanics is a key factor to be investigated to improve the knowledge of how the overall trabecular structure reacts to loading and overloading. The aim of this study was to develop a new device for measuring the mechanical competence of single trabeculae in the post-yield region for bo...

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Veröffentlicht in:	Journal of the mechanical behavior of biomedical materials 2013-04, Vol.20, p.6-18
Hauptverfasser:	Carretta, Roberto, Luisier, Benoit, Bernoulli, Daniel, Stüssi, Edgar, Müller, Ralph, Lorenzetti, Silvio
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Animals Bend tests Bone mechanics Bone quality Cattle Degradation Elastic modulus Elastic Modulus - physiology Equipment Design Equipment Failure Analysis Femur - cytology Femur - physiology Finite element method Image Interpretation, Computer-Assisted - instrumentation Mechanical properties Microscopy, Confocal - instrumentation Models, Biological Modulus of elasticity Non linear mechanics Physical Stimulation - instrumentation Raman spectroscopy Reproducibility of Results Sensitivity and Specificity Strain Stress, Mechanical Tensile Strength - physiology Trabecular bone Weight-Bearing - physiology
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Beschreibung
Zusammenfassung:	Tissue level mechanics is a key factor to be investigated to improve the knowledge of how the overall trabecular structure reacts to loading and overloading. The aim of this study was to develop a new device for measuring the mechanical competence of single trabeculae in the post-yield region for both tensile and bending tests, characterized by high accuracy and precision, and to assess the effect of testing mode, donor age and material composition. A novel approach for measuring the displacement and deformation was developed (accuracy error of 0.3% and a precision of 2.7%). A total of 30 samples from two bovine femora of different ages (from
ISSN:	1751-6161 1878-0180
DOI:	10.1016/j.jmbbm.2012.12.003