Synthesis of 2-cyanoacryloyl chloride and its interaction with O- and S-nucleophiles

Synthesis of 2-cyanoacryloyl chloride and its interaction with O- and S-nucleophiles

Reaction of 2-cyanoacrylic acid with oxalyl chloride gives quantitatively 2-cyanoacryloyl chloride capable of esterifying thiols and fluorinated alcohols.

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Bibliographische Detailangaben
Veröffentlicht in:Mendeleev communications 2013-11, Vol.23 (6), p.356-357
Hauptverfasser: Dyatlov, Valerie A., Rustamov, Iskander R., Grebeneva, Tatiana A., Maleev, Viktor I., Gololobov, Yuri G., Kireev, Vyacheslav V.
Format: Artikel
Sprache:eng
Schlagworte:
Alcohols
Chlorides
Esterification
Fluorination
Synthesis
Thiols
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Zusammenfassung:Reaction of 2-cyanoacrylic acid with oxalyl chloride gives quantitatively 2-cyanoacryloyl chloride capable of esterifying thiols and fluorinated alcohols.
ISSN:0959-9436
DOI:10.1016/j.mencom.2013.11.019