New parameters for identifying subclinical atherosclerosis in patients with primary Sjögren's syndrome: a pilot study

We investigated sub-clinical cardiovascular involvement in primary Sjögren's syndrome (pSS) patients by means of ADMA, coronary flow reserve (CFR), intima media thickness (cIMT), pulse wave velocity (PWV) and myocardial deformation. The study involved 22 outpatients with pSS (6 males, 16 female...

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Veröffentlicht in:	Clinical and experimental rheumatology 2014-05, Vol.32 (3), p.361-368
Hauptverfasser:	Atzeni, F, Sarzi-Puttini, P, Signorello, M C, Gianturco, L, Stella, D, Boccassini, L, Ricci, C, Bodini, B D, Batticciotto, A, De Gennaro-Colonna, V, Drago, L, Turiel, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Arginine - analogs & derivatives Arginine - blood Atherosclerosis - diagnostic imaging Atherosclerosis - epidemiology Atherosclerosis - physiopathology Carotid Intima-Media Thickness Coronary Circulation - physiology Echocardiography Endothelium, Vascular - physiopathology Female Humans Male Middle Aged Pilot Projects Pulse Wave Analysis Risk Factors Sjogren's Syndrome - diagnostic imaging Sjogren's Syndrome - epidemiology Sjogren's Syndrome - physiopathology Vascular Stiffness - physiology
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Zusammenfassung:	We investigated sub-clinical cardiovascular involvement in primary Sjögren's syndrome (pSS) patients by means of ADMA, coronary flow reserve (CFR), intima media thickness (cIMT), pulse wave velocity (PWV) and myocardial deformation. The study involved 22 outpatients with pSS (6 males, 16 females; mean age 60.14±7.81 years) and no documentable cardiovascular disease, and 22 age- and gender-matched controls. Dipyridamole transthoracic stress echocardiography was used to evaluate wall motion and CFR. A CFR value of
ISSN:	0392-856X