A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammation

A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammation

Visualization of macrophages in live animals has been of great interest for a better understanding of inflammation. We developed a near infrared (NIR) probe that can selectively detect macrophages and visualize inflammation in vivo using the IVIS spectrum, Fluorescence Molecular Tomography (FMT) and...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2014-06, Vol.50 (50), p.6589-6591
Hauptverfasser: Kang, Nam-Young, Park, Sung-Jin, Ang, Xiao Wei Emmiline, Samanta, Animesh, Driessen, Wouter H P, Ntziachristos, Vasilis, Vasquez, Kristine O, Peterson, Jeffrey D, Yun, Seong-Wook, Chang, Young-Tae
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Cells, Cultured
Diagnostic Imaging
Fluorescent Dyes
Inflammation - diagnosis
Macrophages - pathology
Mice
Spectroscopy, Near-Infrared
Tomography
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Zusammenfassung:Visualization of macrophages in live animals has been of great interest for a better understanding of inflammation. We developed a near infrared (NIR) probe that can selectively detect macrophages and visualize inflammation in vivo using the IVIS spectrum, Fluorescence Molecular Tomography (FMT) and Multi-Spectral Optoacoustic Tomography (MSOT).
ISSN:1359-7345
1364-548X
DOI:10.1039/c4cc02038c