Long-term survival after surgical resection for huge hepatocellular carcinoma: Comparison with transarterial chemoembolization after propensity score matching

Long-term survival after surgical resection for huge hepatocellular carcinoma: Comparison with transarterial chemoembolization after propensity score matching

Background and Aims Surgical resection (SR) and transarterial chemoembolization (TACE) have been commonly applied for patients with huge hepatocellular carcinoma (HCC). However, optimal treatment has not been established. Methods Between 2000 and 2009, 267 patients with huge HCC (≥ 10 cm) underwent...

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Veröffentlicht in:Journal of gastroenterology and hepatology 2014-05, Vol.29 (5), p.1043-1048
Hauptverfasser: Min, Yang Won, Lee, Jun Hee, Gwak, Geum-Youn, Paik, Yong Han, Lee, Joon Hyoek, Rhee, Poong-Lyul, Koh, Kwang Cheol, Paik, Seung Woon, Yoo, Byung Chul, Choi, Moon Seok
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Carcinoma, Hepatocellular - mortality
Carcinoma, Hepatocellular - surgery
Carcinoma, Hepatocellular - therapy
Chemoembolization, Therapeutic
Cohort Studies
Female
Follow-Up Studies
Hepatectomy - mortality
huge hepatocellular carcinoma
Humans
Liver Neoplasms - mortality
Liver Neoplasms - surgery
Liver Neoplasms - therapy
Male
Middle Aged
Multivariate Analysis
Propensity Score
surgical resection
Survival Rate
Time Factors
transarterial chemoembolization
Treatment Outcome
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Zusammenfassung:Background and Aims Surgical resection (SR) and transarterial chemoembolization (TACE) have been commonly applied for patients with huge hepatocellular carcinoma (HCC). However, optimal treatment has not been established. Methods Between 2000 and 2009, 267 patients with huge HCC (≥ 10 cm) underwent TACE and 84 underwent SR as the first treatment. Propensity score matching generated a matched cohort composed of 152 patients. We investigated overall survival and possible prognostic factors. Results At baseline, the surgery group showed a tendency to have solitary tumor (72.6% vs 39.3%, P 
ISSN:0815-9319
1440-1746
DOI:10.1111/jgh.12504