Electrochemical and cellular behavior of ultrafine-grained titanium in vitro

The electrochemical and cellular behavior of commercially pure titanium (CP-Ti) with both ultrafine-grained (UFG) and coarse-grained (CG) microstructure was evaluated in this study. Equal channel angular pressing was used to produce the UFG structure titanium. Polarization and electrochemical impedance tests were carried out in a simulated body fluid (SBF) at 37°C. Cellular behaviors of samples were assessed using fibroblast cells. Results of the investigations illustrate the improvement of both corrosion and biological behavior of UFG CP-Ti in comparison with the CG counterpart. [Display omitted] •Equal channel angular pressing was used to produce the UFG structured titanium.•The electrochemical behavior of Ti samples in simulated body fluid was evaluated.•Cellular behavior of Ti samples was assessed using fibroblast cellules.•Corrosion and biological behaviors of UFG-Ti were improved in comparison with CG-Ti.