Chemistry of Toromycin

Chemical degradation and spectral studies on toromycin, an antibiotic isolated from Streptomyces collinus subsp. albescens, showed that toromycin is a polycyclic aromatic hydrocarbon having a C-glycosyl group at C-4, a vinyl group at C-8, two methoxyl groups at C-10 and C-12, and a phenolic hydroxyl...

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Veröffentlicht in:Chemical & pharmaceutical bulletin 1980/12/25, Vol.28(12), pp.3601-3611
Hauptverfasser: HORII, SATOSHI, FUKASE, HIROSHI, MIZUTA, EIJI, HATANO, KAZUNORI, MIZUNO, KOMEI
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Sprache:eng
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Zusammenfassung:Chemical degradation and spectral studies on toromycin, an antibiotic isolated from Streptomyces collinus subsp. albescens, showed that toromycin is a polycyclic aromatic hydrocarbon having a C-glycosyl group at C-4, a vinyl group at C-8, two methoxyl groups at C-10 and C-12, and a phenolic hydroxyl group at C-1 of 6-oxo-6H-benzo [d] naphtho-[1, 2-b] pyran (1).
ISSN:0009-2363
1347-5223
DOI:10.1248/cpb.28.3601