Risk factors for the acquisition of carbapenem-resistant Escherichia coli at a tertiary care center in South Korea: A matched case-control study

Background Carbapenem resistance among gram-negative bacilli is an emerging threat worldwide. The objective of this study was to identify risk factors for the acquisition of carbapenem-resistant Escherichia coli (CRE). Methods We conducted a matched case-control study comprising 57 cases of acquisit...

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Veröffentlicht in:	American journal of infection control 2014-06, Vol.42 (6), p.621-625
Hauptverfasser:	Ahn, Jin Young, MD, Song, Je Eun, MD, Kim, Min Hyung, MD, Choi, Heun, MD, Kim, Jae Kyung, MD, Ann, Hea Won, MD, Kim, Jung Ho, MD, Jeon, Yongduk, MD, Jeong, Su Jin, MD, PhD, Kim, Sun Bean, MD, Ku, Nam Su, MD, Han, Sang Hoon, MD, PhD, Song, Young Goo, MD, PhD, Yong, Dongeun, MD, PhD, Lee, Kyungwon, MD, PhD, Kim, June Myung, MD, PhD, Choi, Jun Yong, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Antibacterial agents Antibiotic selective pressure Antibiotics. Antiinfectious agents. Antiparasitic agents beta-Lactam Resistance Biological and medical sciences Carbapenem resistance Carbapenems - pharmacology Carbapenems - therapeutic use Case-Control Studies Cross Infection - epidemiology Cross Infection - microbiology Disease control Drug resistance E coli Epidemiology. Vaccinations Escherichia coli - drug effects Escherichia coli Infections - epidemiology Escherichia coli Infections - microbiology Female Fluoroquinolones - therapeutic use General aspects Hospitals Humans Infection Control Infectious Disease Infectious diseases Length of Stay Male Medical sciences Microbial Sensitivity Tests Middle Aged Nosocomial infections Pharmacology. Drug treatments Republic of Korea - epidemiology Retrospective Studies Risk Factors Tertiary Care Centers
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Zusammenfassung:	Background Carbapenem resistance among gram-negative bacilli is an emerging threat worldwide. The objective of this study was to identify risk factors for the acquisition of carbapenem-resistant Escherichia coli (CRE). Methods We conducted a matched case-control study comprising 57 cases of acquisition of CRE and 114 controls (1:2 matched) selected from patients with a culture of carbapenem-susceptible E coli between January 2006 and December 2010 at a 2000-bed tertiary care center in South Korea. Results On univariate analysis, previous use of carbapenem ( P
ISSN:	0196-6553 1527-3296
DOI:	10.1016/j.ajic.2014.02.024