The effect of phenobarbitone on cognition in adult patients with new onset epilepsy: A multi-centric prospective study from India

Highlights • 75 adults with epilepsy on phenobarbitone underwent serial neuropsychological assessment. • Phenobarbitone was effective, and well tolerated AED. • No deterioration rather an improvement of neuropsychological functions. • There was distinct improvement in psychosocial functioning....

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Veröffentlicht in:	Epilepsy research 2014-07, Vol.108 (5), p.928-936
Hauptverfasser:	Satischandra, P, Rao, S.L, Ravat, S, Jayalakhsmi, S, Senapathy, A, Shah, Urvashi, Shunmukhi, M.S, Dutta, Aparna, Mukaddam, Q, Naik, M, Subbakrishna, D.K, Sinha, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anticonvulsants - adverse effects Anticonvulsants - therapeutic use Biological and medical sciences Cognition Cognition - drug effects Epilepsy - drug therapy Epilepsy - physiopathology Epilepsy - psychology Female Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans India Male Medical sciences Nervous system (semeiology, syndromes) Neurology Neuropsychological assessment Neuropsychological Tests Phenobarbital - adverse effects Phenobarbital - therapeutic use Phenobarbitone Prospective Studies Seizures - drug therapy Seizures - physiopathology Seizures - psychology Time Factors Treatment Outcome
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Zusammenfassung:	Highlights • 75 adults with epilepsy on phenobarbitone underwent serial neuropsychological assessment. • Phenobarbitone was effective, and well tolerated AED. • No deterioration rather an improvement of neuropsychological functions. • There was distinct improvement in psychosocial functioning.
ISSN:	0920-1211 1872-6844
DOI:	10.1016/j.eplepsyres.2014.03.012