Functional and morphological alterations following irradiation of isolated rat stomach: a model for estimation of radiation injury

Radiation exposure of the stomach is associated with functional and morphological changes. Earlier experimental data were mainly obtained from studies of whole- or partial-body irradiated animals. In the present study, the authors investigated the effects of 3-30 Gy irradiation on the surgically exp...

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Veröffentlicht in:	Pharmacology & therapeutics (Oxford) 1988, Vol.39 (1), p.85-87
Hauptverfasser:	Weshler, Z., Ligumski, M., Tochner, Z., Kopolovic, J., Carmeli, F., Rachmilewitz, D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alprostadil - analogs & derivatives Alprostadil - therapeutic use Animals Gastric Acid - metabolism Male Misoprostol Models, Biological Radiation Injuries, Experimental - pathology Radiation Injuries, Experimental - prevention & control Radiation-Protective Agents Rats Rats, Inbred Strains Stomach - pathology Stomach - radiation effects Sucralfate - therapeutic use
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Radiation exposure of the stomach is associated with functional and morphological changes. Earlier experimental data were mainly obtained from studies of whole- or partial-body irradiated animals. In the present study, the authors investigated the effects of 3-30 Gy irradiation on the surgically exposed rat stomach and the radioprotective effect of sucralfate and misoprostol on the irradiated stomach.
ISSN:	0163-7258 1879-016X
DOI:	10.1016/0163-7258(88)90043-5