Abscess within a meningioma: pathogenesis and rare case report

[8],[9] We postulate that these very reasons and others make them susceptible to abscess formation: (1) Meningioma vascularity: (a) Predominant meningeal blood supply and being outside the blood brain barrier, (b) increased vasculature, making them act as sieves filtering out the pathogens in bacter...

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Veröffentlicht in:Neurology India 2014-03, Vol.62 (2), p.196-198
Hauptverfasser: Krishnan, Shyam Sundar, Panigrahi, Manas, Pattanagare, Satvik G, Varma, Ravi D, Rao, Satish I
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Sprache:eng
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Zusammenfassung:[8],[9] We postulate that these very reasons and others make them susceptible to abscess formation: (1) Meningioma vascularity: (a) Predominant meningeal blood supply and being outside the blood brain barrier, (b) increased vasculature, making them act as sieves filtering out the pathogens in bacteremia, (c) the flow pattern: Main supplying artery entering the meningioma does not branch until it reaches the center where it bifurcates into arterioles and capillaries; hence, the entire branching to the periphery originates at the center giving adequate time for the pathogen to lodge and get entrapped, and (d) in case of parasagittal and falcine locations mainly due to the compression/occlusion of the draining veins hence stagnates the blood in the meningioma giving further chance for harboring the pathogen; (2) absence of the blood brain barrier; (3) absence of immune response; (4) rich nutritive environment, rich in lipids and glycogen with its indolent growth rate.
ISSN:0028-3886
1998-4022
DOI:10.4103/0028-3886.132398