Reduced incidence of invasive pneumococcal disease after introduction of the 13-valent conjugate vaccine in Navarre, Spain, 2001–2013

Highlights • We analyse the trend of invasive pneumococcal disease in the 13-valent vaccine era. • The incidence of cases has declined notably in children and moderately in adults. • The incidence of cases due to vaccine serotypes decreased 81% in children

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Veröffentlicht in:	Vaccine 2014-05, Vol.32 (22), p.2553-2562
Hauptverfasser:	Guevara, Marcela, Ezpeleta, Carmen, Gil-Setas, Alberto, Torroba, Luis, Beristain, Xabier, Aguinaga, Aitziber, García-Irure, José Javier, Navascués, Ana, García-Cenoz, Manuel, Castilla, Jesús
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Allergy and Immunology Applied microbiology Bacterial diseases Bacteriology Biological and medical sciences Child Child, Preschool Children & youth Female Fundamental and applied biological sciences. Psychology Human bacterial diseases Humans Immunization Impact Incidence Infant Infectious diseases Invasive pneumococcal disease Male Medical sciences Meningitis Microbiology Middle Aged Miscellaneous Pneumococcal conjugate vaccine Pneumococcal Infections - epidemiology Pneumococcal Infections - prevention & control Pneumococcal Vaccines - administration & dosage Pneumonia Public health surveillance Sentinel Surveillance Spain - epidemiology Staphylococcal infections, streptococcal infections, pneumococcal infections Streptococcus pneumoniae Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Vaccines, Conjugate - administration & dosage Young Adult
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Beschreibung
Zusammenfassung:	Highlights • We analyse the trend of invasive pneumococcal disease in the 13-valent vaccine era. • The incidence of cases has declined notably in children and moderately in adults. • The incidence of cases due to vaccine serotypes decreased 81% in children
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2014.03.054