Breaking down the wall: the nuclear envelope during mitosis

Highlights • The nuclear envelope (NE) is actively remodeled during mitosis. • Microtubule-organizing centers (MTOCs) insert into the NE in closed mitosis. • The NE disassembles during open mitosis to facilitate spindle formation. • Membrane bending, composition and stabilization are associated with...

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Veröffentlicht in:	Current opinion in cell biology 2014-02, Vol.26, p.1-9
Hauptverfasser:	Smoyer, Christine J, Jaspersen, Sue L
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Transport Cytoplasm - genetics Cytoplasm - metabolism Eukaryotic Cells - cytology Eukaryotic Cells - metabolism Humans Internal Medicine Mitosis Nuclear Envelope - chemistry Nuclear Envelope - genetics Nuclear Envelope - metabolism Nuclear Pore - metabolism
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Beschreibung
Zusammenfassung:	Highlights • The nuclear envelope (NE) is actively remodeled during mitosis. • Microtubule-organizing centers (MTOCs) insert into the NE in closed mitosis. • The NE disassembles during open mitosis to facilitate spindle formation. • Membrane bending, composition and stabilization are associated with MTOCs.
ISSN:	0955-0674 1879-0410
DOI:	10.1016/j.ceb.2013.08.002