Programmed necrosis in microbial pathogenesis

Programmed necrosis in microbial pathogenesis

Highlights • Programmed necrosis is an emerging component of host–pathogen interactions. • Viruses and bacteria trigger programmed necrosis via multiple pathways. • Programmed necrosis can be an effective host response or a pathogen strategy for exploitation. • Pathogen-induced necrosis influences v...

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Veröffentlicht in:Trends in microbiology (Regular ed.) 2014-04, Vol.22 (4), p.199-207
Hauptverfasser: Sridharan, Haripriya, Upton, Jason W
Format: Artikel
Sprache:eng
Schlagworte:
Bacteria - pathogenicity
cell death
Coxsackie B virus
EPEC
host defense
Host-Pathogen Interactions
Human adenovirus
influenza
innate immunity
Internal Medicine
IRF3
Listeria
MCMV
Mycobacterium
necroptosis
Necrosis
PKR
reovirus
RIP1
RIP3
Salmonella
TNF
vaccinia
Virulence
Viruses - pathogenicity
Yersinia
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Beschreibung
Zusammenfassung:Highlights • Programmed necrosis is an emerging component of host–pathogen interactions. • Viruses and bacteria trigger programmed necrosis via multiple pathways. • Programmed necrosis can be an effective host response or a pathogen strategy for exploitation. • Pathogen-induced necrosis influences virulence and disease pathology.
ISSN:0966-842X
1878-4380
DOI:10.1016/j.tim.2014.01.005