Tympanic Paraganglioma
[...]even with such a classic presentation of a glomus tympanicum, an aberrant carotid artery, highriding jugular bulb, and glomus jugulare must also be considered.2 The best diagnostic tool to investigate pulsatile tinnitus with a visible retroor intratympanic mass is a high-resolution CT scan of t...
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| Veröffentlicht in: | Ear, nose, & throat journal nose, & throat journal, 2014-04, Vol.93 (4-5), p.136-138 |
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| container_title | Ear, nose, & throat journal |
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| creator | Blake, Danielle M. Tomovic, Senja Jyung, Robert W. |
| description | [...]even with such a classic presentation of a glomus tympanicum, an aberrant carotid artery, highriding jugular bulb, and glomus jugulare must also be considered.2 The best diagnostic tool to investigate pulsatile tinnitus with a visible retroor intratympanic mass is a high-resolution CT scan of the temporal bones, since it can precisely define the location and extent of the tumor.2 Treatment options include observation, radiation therapy, or surgical excision with or without preoperative angioembolization. Since chronically hypoxic patients often develop paragangliomas arising from the carotid body, a critical site of oxygen sensing, activation of hypoxia-inducible pathways appears to be essential to the pathogenesis of these tumors and may greatly contribute to their hypervascularity. [...]when evaluating patients with paragangliomas, it is important to take a careful history and document all risk factors for chronic hypoxia, including living at a high altitude, chronic obstructive pulmonary disease, and sleep apnea. |
| doi_str_mv | 10.1177/0145561314093004-503 |
| format | Article |
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Since chronically hypoxic patients often develop paragangliomas arising from the carotid body, a critical site of oxygen sensing, activation of hypoxia-inducible pathways appears to be essential to the pathogenesis of these tumors and may greatly contribute to their hypervascularity. 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Since chronically hypoxic patients often develop paragangliomas arising from the carotid body, a critical site of oxygen sensing, activation of hypoxia-inducible pathways appears to be essential to the pathogenesis of these tumors and may greatly contribute to their hypervascularity. [...]when evaluating patients with paragangliomas, it is important to take a careful history and document all risk factors for chronic hypoxia, including living at a high altitude, chronic obstructive pulmonary disease, and sleep apnea.</description><subject>Ear diseases</subject><subject>Ear Neoplasms - complications</subject><subject>Ear Neoplasms - diagnosis</subject><subject>Ear Neoplasms - surgery</subject><subject>Ears & hearing</subject><subject>Female</subject><subject>Hearing loss</subject><subject>Hearing Loss, Mixed Conductive-Sensorineural - etiology</subject><subject>Humans</subject><subject>Hypoxia</subject><subject>Middle Aged</subject><subject>Mutation</subject><subject>Otoscopy</subject><subject>Paraganglioma - complications</subject><subject>Paraganglioma - diagnosis</subject><subject>Paraganglioma - surgery</subject><subject>Patients</subject><subject>Radiation therapy</subject><subject>Sleep</subject><subject>Sleep apnea</subject><subject>Tinnitus - etiology</subject><subject>Tomography, X-Ray Computed</subject><subject>Tympanic Membrane - diagnostic imaging</subject><subject>Tympanic Membrane - pathology</subject><subject>Tympanic Membrane - surgery</subject><issn>0145-5613</issn><issn>1942-7522</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNp90c9LwzAUB_AgipvTqycRQRAvnXlJmqbHMfwFAz3sHtI07TraZibtYf-9GZuyyZAcAuHzfS-8h9AN4DFAkjxhYHHMgQLDKcWYRTGmJ2gIKSNREhNyioYbEm3MAF14v8Q4PHA4RwPCBCSEwBBdz9fNSrWVvvtUTpWqLevKNuoSnRWq9uZqd4_Q_OV5Pn2LZh-v79PJLNKMky4yNKFUpzhNFCdMZRqYKDTXIi8yJmJGBY4zHDrhPMdccWpYlkMqNElTTAUdocdt2ZWzX73xnWwqr01dq9bY3kuICYOEC4gDvf9Dl7Z3bfhcUBRzHrrtqVLVRlZtYTun9KaonFAueMLDCIKKjqjStMap2ramqMLzgR8f8eHkpqn00cDDXmBhVN0tvK37rrKtP4RsC7Wz3jtTyJWrGuXWErDcrFn-XbMMaw6x290w-qwx-W_oZ68BwBZ4VZq9Sf1X9BuTvKkf</recordid><startdate>201404</startdate><enddate>201404</enddate><creator>Blake, Danielle M.</creator><creator>Tomovic, Senja</creator><creator>Jyung, Robert W.</creator><general>SAGE Publications</general><general>Sage Publications, Inc</general><general>SAGE PUBLICATIONS, INC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>4T-</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>201404</creationdate><title>Tympanic Paraganglioma</title><author>Blake, Danielle M. ; Tomovic, Senja ; Jyung, Robert W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c462t-e3733c9097a624abc148fc6c8dfb48543805b07220dd06a63e4bd198c2990383</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Ear diseases</topic><topic>Ear Neoplasms - complications</topic><topic>Ear Neoplasms - diagnosis</topic><topic>Ear Neoplasms - surgery</topic><topic>Ears & hearing</topic><topic>Female</topic><topic>Hearing loss</topic><topic>Hearing Loss, Mixed Conductive-Sensorineural - etiology</topic><topic>Humans</topic><topic>Hypoxia</topic><topic>Middle Aged</topic><topic>Mutation</topic><topic>Otoscopy</topic><topic>Paraganglioma - complications</topic><topic>Paraganglioma - diagnosis</topic><topic>Paraganglioma - surgery</topic><topic>Patients</topic><topic>Radiation therapy</topic><topic>Sleep</topic><topic>Sleep apnea</topic><topic>Tinnitus - etiology</topic><topic>Tomography, X-Ray Computed</topic><topic>Tympanic Membrane - diagnostic imaging</topic><topic>Tympanic Membrane - pathology</topic><topic>Tympanic Membrane - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Blake, Danielle M.</creatorcontrib><creatorcontrib>Tomovic, Senja</creatorcontrib><creatorcontrib>Jyung, Robert W.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Docstoc</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Ear, nose, & throat journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Blake, Danielle M.</au><au>Tomovic, Senja</au><au>Jyung, Robert W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Tympanic Paraganglioma</atitle><jtitle>Ear, nose, & throat journal</jtitle><addtitle>Ear Nose Throat J</addtitle><date>2014-04</date><risdate>2014</risdate><volume>93</volume><issue>4-5</issue><spage>136</spage><epage>138</epage><pages>136-138</pages><issn>0145-5613</issn><eissn>1942-7522</eissn><coden>ENTJDO</coden><abstract>[...]even with such a classic presentation of a glomus tympanicum, an aberrant carotid artery, highriding jugular bulb, and glomus jugulare must also be considered.2 The best diagnostic tool to investigate pulsatile tinnitus with a visible retroor intratympanic mass is a high-resolution CT scan of the temporal bones, since it can precisely define the location and extent of the tumor.2 Treatment options include observation, radiation therapy, or surgical excision with or without preoperative angioembolization. Since chronically hypoxic patients often develop paragangliomas arising from the carotid body, a critical site of oxygen sensing, activation of hypoxia-inducible pathways appears to be essential to the pathogenesis of these tumors and may greatly contribute to their hypervascularity. [...]when evaluating patients with paragangliomas, it is important to take a careful history and document all risk factors for chronic hypoxia, including living at a high altitude, chronic obstructive pulmonary disease, and sleep apnea.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>24817221</pmid><doi>10.1177/0145561314093004-503</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0145-5613 |
| ispartof | Ear, nose, & throat journal, 2014-04, Vol.93 (4-5), p.136-138 |
| issn | 0145-5613 1942-7522 |
| language | eng |
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| source | Sage Journals GOLD Open Access 2024 |
| subjects | Ear diseases Ear Neoplasms - complications Ear Neoplasms - diagnosis Ear Neoplasms - surgery Ears & hearing Female Hearing loss Hearing Loss, Mixed Conductive-Sensorineural - etiology Humans Hypoxia Middle Aged Mutation Otoscopy Paraganglioma - complications Paraganglioma - diagnosis Paraganglioma - surgery Patients Radiation therapy Sleep Sleep apnea Tinnitus - etiology Tomography, X-Ray Computed Tympanic Membrane - diagnostic imaging Tympanic Membrane - pathology Tympanic Membrane - surgery |
| title | Tympanic Paraganglioma |
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