Tympanic Paraganglioma

[...]even with such a classic presentation of a glomus tympanicum, an aberrant carotid artery, highriding jugular bulb, and glomus jugulare must also be considered.2 The best diagnostic tool to investigate pulsatile tinnitus with a visible retroor intratympanic mass is a high-resolution CT scan of t...

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Veröffentlicht in:Ear, nose, & throat journal nose, & throat journal, 2014-04, Vol.93 (4-5), p.136-138
Hauptverfasser: Blake, Danielle M., Tomovic, Senja, Jyung, Robert W.
Format: Artikel
Sprache:eng
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Zusammenfassung:[...]even with such a classic presentation of a glomus tympanicum, an aberrant carotid artery, highriding jugular bulb, and glomus jugulare must also be considered.2 The best diagnostic tool to investigate pulsatile tinnitus with a visible retroor intratympanic mass is a high-resolution CT scan of the temporal bones, since it can precisely define the location and extent of the tumor.2 Treatment options include observation, radiation therapy, or surgical excision with or without preoperative angioembolization. Since chronically hypoxic patients often develop paragangliomas arising from the carotid body, a critical site of oxygen sensing, activation of hypoxia-inducible pathways appears to be essential to the pathogenesis of these tumors and may greatly contribute to their hypervascularity. [...]when evaluating patients with paragangliomas, it is important to take a careful history and document all risk factors for chronic hypoxia, including living at a high altitude, chronic obstructive pulmonary disease, and sleep apnea.
ISSN:0145-5613
1942-7522
DOI:10.1177/0145561314093004-503