In situ hybridization localizes the human putative oncogene gli to chromosome subbands 12q13.3-14.1

In situ hybridization localizes the human putative oncogene gli to chromosome subbands 12q13.3-14.1

Using in situ hybridization, the authors have localized the human putative oncogene gli to chromosome subbands 12q13.3-14.1. The precise genomic sites is of interest since the region 12q13-15 has been found to be consistently rearranged in neoplasia-associated chromosome abnormalities in lipomas, my...

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Veröffentlicht in:Human genetics 1989-01, Vol.82 (2), p.1-2
Hauptverfasser: Arheden, K, Roenne, M, Mandahl, N, Heim, S, Kinzler, K W, Vogelstein, B, Mitelman, F
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Sprache:eng
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Zusammenfassung:Using in situ hybridization, the authors have localized the human putative oncogene gli to chromosome subbands 12q13.3-14.1. The precise genomic sites is of interest since the region 12q13-15 has been found to be consistently rearranged in neoplasia-associated chromosome abnormalities in lipomas, myxoid liposarcomas, uterine leiomyomas, and pleomorphic adenomas of the salivary gland.
ISSN:0340-6717