Clinical Outcome of Isolated Locoregional Recurrence in Patients With Breast Cancer According to Their Primary Local Treatment

Micro-Abstract The long-term clinical outcome was studied for 220 patients with breast cancer who developed isolated locoregional recurrence. Based on a multivariate analysis including multiple pathologic and clinical parameters, the results suggest that patients who had breast-conserving surgery an...

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Veröffentlicht in:	Clinical breast cancer 2014-06, Vol.14 (3), p.198-204
Hauptverfasser:	Shenouda, Mina N, Sadek, Betro T, Goldberg, Saveli I, Keruakous, Amany R, Croft, Brandon J, Abi Raad, Rita F, Taghian, Alphonse G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Breast cancer Breast Neoplasms - mortality Breast Neoplasms - pathology Breast Neoplasms - therapy Combined Modality Therapy Disease-Free Survival Female Hematology, Oncology and Palliative Medicine Humans Isolated locoregional recurrence Kaplan-Meier Estimate Local breast treatment Long-term clinical outcome Mastectomy, Segmental Middle Aged Neoplasm Recurrence, Local - mortality Neoplasm Recurrence, Local - therapy Obstetrics and Gynecology Prognosis Prognostic variables Proportional Hazards Models Radiotherapy, Adjuvant
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Zusammenfassung:	Micro-Abstract The long-term clinical outcome was studied for 220 patients with breast cancer who developed isolated locoregional recurrence. Based on a multivariate analysis including multiple pathologic and clinical parameters, the results suggest that patients who had breast-conserving surgery and radiation therapy for their primary tumor have a significantly better clinical outcome compared with those who had mastectomy with no radiation therapy.
ISSN:	1526-8209 1938-0666
DOI:	10.1016/j.clbc.2013.12.007