Preoperative Increasing C-reactive Protein Affects the Outcome for Active Infective Endocarditis

Purpose: This study aimed to determine if preoperative time course changes in serum C-reactive protein (CRP) levels can predict clinical outcome of surgical intervention for active infective endocarditis. Methods: Surgically treated patients (n = 109) with active infective endocarditis were reviewed...

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Veröffentlicht in:Annals of Thoracic and Cardiovascular Surgery 2014, Vol.20(1), pp.48-54
Hauptverfasser: Okada, Yuko, Hosono, Mitsuharu, Sasaki, Yasuyuki, Hirai, Hidekazu, Suehiro, Shigefumi
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Sprache:eng
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Zusammenfassung:Purpose: This study aimed to determine if preoperative time course changes in serum C-reactive protein (CRP) levels can predict clinical outcome of surgical intervention for active infective endocarditis. Methods: Surgically treated patients (n = 109) with active infective endocarditis were reviewed retrospectively. We divided the patients into 2 subgroups according to preoperative transition of increasing or decreasing serum CRP levels, and performed a comparative study. The increasing CRP group included 29 patients and the decreasing CRP group included 80 patients. Results: There were more patients with methicillin-resistant Staphylococcus aureus and New York Heart Association functional class IV in the increasing CRP group. Hospital mortality was signifi cantly higher in the increasing CRP group (34.5%) than that in the decreasing CRP group (5.0%) (p
ISSN:1341-1098
2186-1005
DOI:10.5761/atcs.oa.12.02091