Synergistic interactions of various doses of diethylstilbestrol and x-irradiation on mammary neoplasia in female ACI rats

The intent of this study was to investigate the relationship between diethylstilbestrol (DES) dose and its synergistic interaction with X-irradiation for mammary carcinogenesis in ACI rats. In addition, the role of prolactin in this synergism was studied.

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Bibliographische Detailangaben
Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1980-11, Vol.40 (11), p.3966-3972
Hauptverfasser:	Stone, J P, Holtzman, S, Shellabarger, C J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Diethylstilbestrol - administration & dosage Dose-Response Relationship, Drug Dose-Response Relationship, Radiation Drug Implants Female Mammary Neoplasms, Experimental - blood Mammary Neoplasms, Experimental - etiology Prolactin - blood Rats Time Factors X-Rays
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Beschreibung
Zusammenfassung:	The intent of this study was to investigate the relationship between diethylstilbestrol (DES) dose and its synergistic interaction with X-irradiation for mammary carcinogenesis in ACI rats. In addition, the role of prolactin in this synergism was studied.
ISSN:	0008-5472