Comparative toxicity to rats of lead acetate from food or water

It is not clear at present if lead is more toxic when added to food or to water. Because of the general effects of food intake on reduction of lead absorption in humans, it is possible that lead-contaminated water is more toxic than lead-contaminated food. The purpose of this study was to determine...

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Veröffentlicht in:	Bull. Environ. Contam. Toxicol.; (United States) 1980-01, Vol.25 (4), p.541-546
Hauptverfasser:	Mahaffey, K R, Rader, J I, Schaefer, J M, Kramer, S N
Format:	Artikel
Sprache:	eng
Schlagworte:	550500 > Metabolism ACETATES Aminolevulinic Acid - metabolism ANIMALS BASIC BIOLOGICAL SCIENCES Biological Availability BIOLOGICAL EFFECTS BIOLOGICAL MATERIALS BLOOD BLOOD COUNT BODY BODY FLUIDS Body Weight - drug effects CARBOXYLIC ACID SALTS CARBOXYLIC ACIDS COMPARATIVE EVALUATIONS Drinking - drug effects DRINKING WATER Eating - drug effects ELEMENTS FEMUR FOOD Food Contamination GLOBIN HEMOGLOBIN HETEROCYCLIC ACIDS HETEROCYCLIC COMPOUNDS HISTOLOGY HYDROGEN COMPOUNDS KIDNEYS LEAD Lead - metabolism Lead - toxicity Male MAMMALS MATERIALS METABOLISM METALS ORGANIC ACIDS ORGANIC COMPOUNDS ORGANIC NITROGEN COMPOUNDS ORGANS OXYGEN COMPOUNDS PIGMENTS PORPHYRINS PROTEINS QUANTITY RATIO RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RATS RETENTION RODENTS SENSITIVITY SKELETON SPECTROPHOTOMETRY TIME DEPENDENCE TOXICITY VERTEBRATES VOLTAMETRY WATER 560305 > Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987) Water Pollutants - toxicity Water Pollutants, Chemical - toxicity WEIGHT
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Beschreibung
Zusammenfassung:	It is not clear at present if lead is more toxic when added to food or to water. Because of the general effects of food intake on reduction of lead absorption in humans, it is possible that lead-contaminated water is more toxic than lead-contaminated food. The purpose of this study was to determine if equal concentrations of lead acetate added to food or to water were equally bioavailable to rats.
ISSN:	0007-4861 1432-0800
DOI:	10.1007/BF01985569