Family of human Na super(+),K super(+)-ATPase genes: Structure of the putative regulatory region of the alpha super(+)-gene

Family of human Na super(+),K super(+)-ATPase genes: Structure of the putative regulatory region of the alpha super(+)-gene

The primary structure of the putative regulatory region of a gene of the Na super(+),K super(+)-ATPase multigene family in the human genome has been determined. This region includes the first exon with all of the untranslatable sequence of mRNA and a dozen nucleotides, coding for the first four amin...

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Veröffentlicht in:FEBS letters 1989-01, Vol.244 (2), p.481-483
Hauptverfasser: Sverdlov, ED, Bessarab, DA, Malyshev, I V, Petrukhin, KE, Smirnov, Y V, Ushkaryov, YA, Monastyrskaya, G S, Broude, N E, Modyanov, N N
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Sprache:eng
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Zusammenfassung:The primary structure of the putative regulatory region of a gene of the Na super(+),K super(+)-ATPase multigene family in the human genome has been determined. This region includes the first exon with all of the untranslatable sequence of mRNA and a dozen nucleotides, coding for the first four amino acids of the hypothetic precursor of the alpha super(+)-subunit. The entire region comprises over 1400 bp. The possible role of specific nucleotide blocks within this region in comparison with other genes is discussed.
ISSN:0014-5793