Recurrent Thymoma With Stiff-Person Syndrome and Pure Red Blood Cell Aplasia
Stiff-person syndrome (formerly known as stiff-man syndrome) is a very rare autoimmune and neurogenic disorder, thought to present as a paraneoplastic variant in association with thymoma. Pure red blood cell aplasia is also a paraneoplastic disorder associated with thymoma. Although separate cases o...
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| Veröffentlicht in: | The Annals of thoracic surgery 2014-05, Vol.97 (5), p.1802-1804 |
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| container_title | The Annals of thoracic surgery |
| container_volume | 97 |
| creator | Kobayashi, Rei, MD Kaji, Masahiro, MD Horiuchi, Sho, MD Miyahara, Naofumi, MD Hino, Yumi, MD Suemasu, Keiichi, MD |
| description | Stiff-person syndrome (formerly known as stiff-man syndrome) is a very rare autoimmune and neurogenic disorder, thought to present as a paraneoplastic variant in association with thymoma. Pure red blood cell aplasia is also a paraneoplastic disorder associated with thymoma. Although separate cases of stiff-person syndrome and pure red blood cell aplasia have been reported, we describe here what is to our knowledge the first case of recurrent thymoma with both stiff-person syndrome and pure red blood cell aplasia. We describe the successful treatment of the neurogenic symptoms of stiff-person syndrome and the progressive anemia associated with pure red blood cell aplasia by tumor excision. |
| doi_str_mv | 10.1016/j.athoracsur.2013.07.103 |
| format | Article |
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Pure red blood cell aplasia is also a paraneoplastic disorder associated with thymoma. Although separate cases of stiff-person syndrome and pure red blood cell aplasia have been reported, we describe here what is to our knowledge the first case of recurrent thymoma with both stiff-person syndrome and pure red blood cell aplasia. We describe the successful treatment of the neurogenic symptoms of stiff-person syndrome and the progressive anemia associated with pure red blood cell aplasia by tumor excision.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/j.athoracsur.2013.07.103</identifier><identifier>PMID: 24792276</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Aged, 80 and over ; Cardiothoracic Surgery ; Female ; Follow-Up Studies ; Humans ; Neoplasm Recurrence, Local - diagnosis ; Neoplasm Recurrence, Local - surgery ; Paraneoplastic Syndromes - diagnosis ; Paraneoplastic Syndromes - surgery ; Red-Cell Aplasia, Pure - complications ; Red-Cell Aplasia, Pure - diagnosis ; Red-Cell Aplasia, Pure - surgery ; Reoperation - methods ; Risk Assessment ; Stiff-Person Syndrome - complications ; Stiff-Person Syndrome - diagnosis ; Stiff-Person Syndrome - surgery ; Surgery ; Thymectomy - methods ; Thymoma - diagnosis ; Thymoma - surgery ; Thymus Neoplasms - diagnosis ; Thymus Neoplasms - surgery ; Time Factors ; Tomography, X-Ray Computed - methods ; Treatment Outcome</subject><ispartof>The Annals of thoracic surgery, 2014-05, Vol.97 (5), p.1802-1804</ispartof><rights>The Society of Thoracic Surgeons</rights><rights>2014 The Society of Thoracic Surgeons</rights><rights>Copyright © 2014 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c479t-102ec26ff48f7a2477d3cd5bd205cda917d69ff9457e9686954693f89e5af6fe3</citedby><cites>FETCH-LOGICAL-c479t-102ec26ff48f7a2477d3cd5bd205cda917d69ff9457e9686954693f89e5af6fe3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24792276$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kobayashi, Rei, MD</creatorcontrib><creatorcontrib>Kaji, Masahiro, MD</creatorcontrib><creatorcontrib>Horiuchi, Sho, MD</creatorcontrib><creatorcontrib>Miyahara, Naofumi, MD</creatorcontrib><creatorcontrib>Hino, Yumi, MD</creatorcontrib><creatorcontrib>Suemasu, Keiichi, MD</creatorcontrib><title>Recurrent Thymoma With Stiff-Person Syndrome and Pure Red Blood Cell Aplasia</title><title>The Annals of thoracic surgery</title><addtitle>Ann Thorac Surg</addtitle><description>Stiff-person syndrome (formerly known as stiff-man syndrome) is a very rare autoimmune and neurogenic disorder, thought to present as a paraneoplastic variant in association with thymoma. Pure red blood cell aplasia is also a paraneoplastic disorder associated with thymoma. Although separate cases of stiff-person syndrome and pure red blood cell aplasia have been reported, we describe here what is to our knowledge the first case of recurrent thymoma with both stiff-person syndrome and pure red blood cell aplasia. We describe the successful treatment of the neurogenic symptoms of stiff-person syndrome and the progressive anemia associated with pure red blood cell aplasia by tumor excision.</description><subject>Aged, 80 and over</subject><subject>Cardiothoracic Surgery</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Neoplasm Recurrence, Local - diagnosis</subject><subject>Neoplasm Recurrence, Local - surgery</subject><subject>Paraneoplastic Syndromes - diagnosis</subject><subject>Paraneoplastic Syndromes - surgery</subject><subject>Red-Cell Aplasia, Pure - complications</subject><subject>Red-Cell Aplasia, Pure - diagnosis</subject><subject>Red-Cell Aplasia, Pure - surgery</subject><subject>Reoperation - methods</subject><subject>Risk Assessment</subject><subject>Stiff-Person Syndrome - complications</subject><subject>Stiff-Person Syndrome - diagnosis</subject><subject>Stiff-Person Syndrome - surgery</subject><subject>Surgery</subject><subject>Thymectomy - methods</subject><subject>Thymoma - diagnosis</subject><subject>Thymoma - surgery</subject><subject>Thymus Neoplasms - diagnosis</subject><subject>Thymus Neoplasms - surgery</subject><subject>Time Factors</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>Treatment Outcome</subject><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU9rGzEQxUVJaZy0X6HomMs6-rOSrEsgMW0TMDTEKT0KRRphubsrR9ot-NtHxmkKPfUkxHszb-Y3CGFK5pRQebmd23GTsnVlynNGKJ8TVRX-Ds2oEKyRTOgTNCOE8KbVSpyis1K29cuq_AGdslZpxpScodUDuClnGEb8uNn3qbf4Zxw3eD3GEJp7yCUNeL0ffE49YDt4fD9lwA_g8U2XksdL6Dp8vetsifYjeh9sV-DT63uOfnz98ri8bVbfv90tr1eNq7ljQwkDx2QI7SIoW2dRnjsvnjwjwnmrqfJSh6BboUDLhdSilZqHhQZhgwzAz9HFse8up-cJymj6WFwdxA6QpmKoYJRzygWt1sXR6nIqJUMwuxx7m_eGEnNgabbmL0tzYGmIqgqvpZ9fU6anHvxb4R941XBzNEDd9XeEbIqLMDjwMYMbjU_xf1Ku_mniujhEZ7tfsIeyTVMeKktDTWGGmPXhpoeTUk6oolLwFzhMnsY</recordid><startdate>20140501</startdate><enddate>20140501</enddate><creator>Kobayashi, Rei, MD</creator><creator>Kaji, Masahiro, MD</creator><creator>Horiuchi, Sho, MD</creator><creator>Miyahara, Naofumi, MD</creator><creator>Hino, Yumi, MD</creator><creator>Suemasu, Keiichi, MD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140501</creationdate><title>Recurrent Thymoma With Stiff-Person Syndrome and Pure Red Blood Cell Aplasia</title><author>Kobayashi, Rei, MD ; Kaji, Masahiro, MD ; Horiuchi, Sho, MD ; Miyahara, Naofumi, MD ; Hino, Yumi, MD ; Suemasu, Keiichi, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c479t-102ec26ff48f7a2477d3cd5bd205cda917d69ff9457e9686954693f89e5af6fe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Aged, 80 and over</topic><topic>Cardiothoracic Surgery</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Neoplasm Recurrence, Local - diagnosis</topic><topic>Neoplasm Recurrence, Local - surgery</topic><topic>Paraneoplastic Syndromes - diagnosis</topic><topic>Paraneoplastic Syndromes - surgery</topic><topic>Red-Cell Aplasia, Pure - complications</topic><topic>Red-Cell Aplasia, Pure - diagnosis</topic><topic>Red-Cell Aplasia, Pure - surgery</topic><topic>Reoperation - methods</topic><topic>Risk Assessment</topic><topic>Stiff-Person Syndrome - complications</topic><topic>Stiff-Person Syndrome - diagnosis</topic><topic>Stiff-Person Syndrome - surgery</topic><topic>Surgery</topic><topic>Thymectomy - methods</topic><topic>Thymoma - diagnosis</topic><topic>Thymoma - surgery</topic><topic>Thymus Neoplasms - diagnosis</topic><topic>Thymus Neoplasms - surgery</topic><topic>Time Factors</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kobayashi, Rei, MD</creatorcontrib><creatorcontrib>Kaji, Masahiro, MD</creatorcontrib><creatorcontrib>Horiuchi, Sho, MD</creatorcontrib><creatorcontrib>Miyahara, Naofumi, MD</creatorcontrib><creatorcontrib>Hino, Yumi, MD</creatorcontrib><creatorcontrib>Suemasu, Keiichi, MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kobayashi, Rei, MD</au><au>Kaji, Masahiro, MD</au><au>Horiuchi, Sho, MD</au><au>Miyahara, Naofumi, MD</au><au>Hino, Yumi, MD</au><au>Suemasu, Keiichi, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recurrent Thymoma With Stiff-Person Syndrome and Pure Red Blood Cell Aplasia</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>2014-05-01</date><risdate>2014</risdate><volume>97</volume><issue>5</issue><spage>1802</spage><epage>1804</epage><pages>1802-1804</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><abstract>Stiff-person syndrome (formerly known as stiff-man syndrome) is a very rare autoimmune and neurogenic disorder, thought to present as a paraneoplastic variant in association with thymoma. Pure red blood cell aplasia is also a paraneoplastic disorder associated with thymoma. Although separate cases of stiff-person syndrome and pure red blood cell aplasia have been reported, we describe here what is to our knowledge the first case of recurrent thymoma with both stiff-person syndrome and pure red blood cell aplasia. We describe the successful treatment of the neurogenic symptoms of stiff-person syndrome and the progressive anemia associated with pure red blood cell aplasia by tumor excision.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>24792276</pmid><doi>10.1016/j.athoracsur.2013.07.103</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Aged, 80 and over Cardiothoracic Surgery Female Follow-Up Studies Humans Neoplasm Recurrence, Local - diagnosis Neoplasm Recurrence, Local - surgery Paraneoplastic Syndromes - diagnosis Paraneoplastic Syndromes - surgery Red-Cell Aplasia, Pure - complications Red-Cell Aplasia, Pure - diagnosis Red-Cell Aplasia, Pure - surgery Reoperation - methods Risk Assessment Stiff-Person Syndrome - complications Stiff-Person Syndrome - diagnosis Stiff-Person Syndrome - surgery Surgery Thymectomy - methods Thymoma - diagnosis Thymoma - surgery Thymus Neoplasms - diagnosis Thymus Neoplasms - surgery Time Factors Tomography, X-Ray Computed - methods Treatment Outcome |
| title | Recurrent Thymoma With Stiff-Person Syndrome and Pure Red Blood Cell Aplasia |
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