PcrV antibody protects multi-drug resistant Pseudomonas aeruginosa induced acute lung injury
Highlights • We analyzed the expression level of TTSS in clinically isolated multi-drug resistant Pseudomonas aeruginsoa strains and compared it with susceptible strains. • We investigated the effect of PcrV antibody on multi-drug resistant Pseudomonas aeruginosa induced acute lung injury. • The TTS...
Gespeichert in:
| Veröffentlicht in: | Respiratory physiology & neurobiology 2014-03, Vol.193, p.21-28 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 28 |
|---|---|
| container_issue | |
| container_start_page | 21 |
| container_title | Respiratory physiology & neurobiology |
| container_volume | 193 |
| creator | Wang, Qin Li, Huayin Zhou, Jian Zhong, Ming Zhu, Duming Feng, Nana Liu, Fanglei Bai, Chunxue Song, Yuanlin |
| description | Highlights • We analyzed the expression level of TTSS in clinically isolated multi-drug resistant Pseudomonas aeruginsoa strains and compared it with susceptible strains. • We investigated the effect of PcrV antibody on multi-drug resistant Pseudomonas aeruginosa induced acute lung injury. • The TTSS is comparatively conservative without correlation with antimicrobial resistance. • PcrV antibody could protect multi-drug resistant Pseudomonas aeruginosa induced acute lung injury. |
| doi_str_mv | 10.1016/j.resp.2014.01.001 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1520365713</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1569904814000020</els_id><sourcerecordid>1499144014</sourcerecordid><originalsourceid>FETCH-LOGICAL-c510t-c531a146055325cdf13734b9e83e11f0807880fbb064ca0d88e79cfe7a2a0c2c3</originalsourceid><addsrcrecordid>eNqFkk2L1jAQgIMo7of-AQ_So5fWmSZtUxBBFnWFBRf8OAkhTadLaj9ek0Z4_71T3tWDB80hCckzk_DMCPEMoUDA-uVYBIqHogRUBWABgA_EOepG51hh-5D3Vd3mLSh9Ji5iHBlosJGPxVmpFGpZyXPx7daFr5ldNt-t_TE7hHUjt8VsTtPm8z6ku4wf8XFjJLuNlPp1XhcbM0t855c12swvfXLUZ9aljbIpLXd8NKZwfCIeDXaK9PR-vRRf3r39fHWd33x8_-HqzU3uKoSNZ4kWVQ1VJcvK9QPKRqquJS0JcQANjdYwdB3UylnotaamdQM1trTgSicvxYtTXv7-j0RxM7OPjqbJLrSmaLAqQdZVg_L_qGpbVIqVMlqeUBfWGAMN5hD8bMPRIJi9AGY0ewHMXgADaNgvBz2_z5-6mfo_Ib-NM_DqBBAL-ekpmOg8LezPBzZv-tX_O__rv8Ld5Bfv7PSdjhTHNYWFVRs0sTRgPu0tsHcAKuDBGn4B9P2sWA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1499144014</pqid></control><display><type>article</type><title>PcrV antibody protects multi-drug resistant Pseudomonas aeruginosa induced acute lung injury</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Wang, Qin ; Li, Huayin ; Zhou, Jian ; Zhong, Ming ; Zhu, Duming ; Feng, Nana ; Liu, Fanglei ; Bai, Chunxue ; Song, Yuanlin</creator><creatorcontrib>Wang, Qin ; Li, Huayin ; Zhou, Jian ; Zhong, Ming ; Zhu, Duming ; Feng, Nana ; Liu, Fanglei ; Bai, Chunxue ; Song, Yuanlin</creatorcontrib><description>Highlights • We analyzed the expression level of TTSS in clinically isolated multi-drug resistant Pseudomonas aeruginsoa strains and compared it with susceptible strains. • We investigated the effect of PcrV antibody on multi-drug resistant Pseudomonas aeruginosa induced acute lung injury. • The TTSS is comparatively conservative without correlation with antimicrobial resistance. • PcrV antibody could protect multi-drug resistant Pseudomonas aeruginosa induced acute lung injury.</description><identifier>ISSN: 1569-9048</identifier><identifier>EISSN: 1878-1519</identifier><identifier>DOI: 10.1016/j.resp.2014.01.001</identifier><identifier>PMID: 24418353</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Acute Lung Injury - drug therapy ; Acute Lung Injury - etiology ; Acute Lung Injury - pathology ; Acute Lung Injury - therapy ; ADP Ribose Transferases - metabolism ; Animals ; Anti-Bacterial Agents - therapeutic use ; Antibodies, Bacterial - therapeutic use ; Antigens, Bacterial - immunology ; Bacterial Proteins - metabolism ; Bacterial Secretion Systems - physiology ; Bacterial Toxins - immunology ; Bacterial Toxins - metabolism ; Ceftazidime - therapeutic use ; Cytokines - blood ; Drug Resistance, Multiple, Bacterial ; Gene Expression ; Immunization, Passive ; Lung - drug effects ; Lung - immunology ; Lung - pathology ; Mab166 ; Medical Education ; Mice ; Mice, Inbred BALB C ; Multi-drug resistance ; Neutrophils - immunology ; PcrV ; Pore Forming Cytotoxic Proteins - immunology ; Pseudomonas aeruginosa ; Pseudomonas aeruginosa - drug effects ; Pseudomonas aeruginosa - pathogenicity ; Pseudomonas Infections - complications ; Pseudomonas Infections - drug therapy ; Pseudomonas Infections - pathology ; Pseudomonas Infections - therapy ; Pulmonary/Respiratory ; Species Specificity ; Survival Analysis ; Type III secretion system</subject><ispartof>Respiratory physiology & neurobiology, 2014-03, Vol.193, p.21-28</ispartof><rights>Elsevier B.V.</rights><rights>2014 Elsevier B.V.</rights><rights>Copyright © 2014 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c510t-c531a146055325cdf13734b9e83e11f0807880fbb064ca0d88e79cfe7a2a0c2c3</citedby><cites>FETCH-LOGICAL-c510t-c531a146055325cdf13734b9e83e11f0807880fbb064ca0d88e79cfe7a2a0c2c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1569904814000020$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24418353$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Qin</creatorcontrib><creatorcontrib>Li, Huayin</creatorcontrib><creatorcontrib>Zhou, Jian</creatorcontrib><creatorcontrib>Zhong, Ming</creatorcontrib><creatorcontrib>Zhu, Duming</creatorcontrib><creatorcontrib>Feng, Nana</creatorcontrib><creatorcontrib>Liu, Fanglei</creatorcontrib><creatorcontrib>Bai, Chunxue</creatorcontrib><creatorcontrib>Song, Yuanlin</creatorcontrib><title>PcrV antibody protects multi-drug resistant Pseudomonas aeruginosa induced acute lung injury</title><title>Respiratory physiology & neurobiology</title><addtitle>Respir Physiol Neurobiol</addtitle><description>Highlights • We analyzed the expression level of TTSS in clinically isolated multi-drug resistant Pseudomonas aeruginsoa strains and compared it with susceptible strains. • We investigated the effect of PcrV antibody on multi-drug resistant Pseudomonas aeruginosa induced acute lung injury. • The TTSS is comparatively conservative without correlation with antimicrobial resistance. • PcrV antibody could protect multi-drug resistant Pseudomonas aeruginosa induced acute lung injury.</description><subject>Acute Lung Injury - drug therapy</subject><subject>Acute Lung Injury - etiology</subject><subject>Acute Lung Injury - pathology</subject><subject>Acute Lung Injury - therapy</subject><subject>ADP Ribose Transferases - metabolism</subject><subject>Animals</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Antibodies, Bacterial - therapeutic use</subject><subject>Antigens, Bacterial - immunology</subject><subject>Bacterial Proteins - metabolism</subject><subject>Bacterial Secretion Systems - physiology</subject><subject>Bacterial Toxins - immunology</subject><subject>Bacterial Toxins - metabolism</subject><subject>Ceftazidime - therapeutic use</subject><subject>Cytokines - blood</subject><subject>Drug Resistance, Multiple, Bacterial</subject><subject>Gene Expression</subject><subject>Immunization, Passive</subject><subject>Lung - drug effects</subject><subject>Lung - immunology</subject><subject>Lung - pathology</subject><subject>Mab166</subject><subject>Medical Education</subject><subject>Mice</subject><subject>Mice, Inbred BALB C</subject><subject>Multi-drug resistance</subject><subject>Neutrophils - immunology</subject><subject>PcrV</subject><subject>Pore Forming Cytotoxic Proteins - immunology</subject><subject>Pseudomonas aeruginosa</subject><subject>Pseudomonas aeruginosa - drug effects</subject><subject>Pseudomonas aeruginosa - pathogenicity</subject><subject>Pseudomonas Infections - complications</subject><subject>Pseudomonas Infections - drug therapy</subject><subject>Pseudomonas Infections - pathology</subject><subject>Pseudomonas Infections - therapy</subject><subject>Pulmonary/Respiratory</subject><subject>Species Specificity</subject><subject>Survival Analysis</subject><subject>Type III secretion system</subject><issn>1569-9048</issn><issn>1878-1519</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkk2L1jAQgIMo7of-AQ_So5fWmSZtUxBBFnWFBRf8OAkhTadLaj9ek0Z4_71T3tWDB80hCckzk_DMCPEMoUDA-uVYBIqHogRUBWABgA_EOepG51hh-5D3Vd3mLSh9Ji5iHBlosJGPxVmpFGpZyXPx7daFr5ldNt-t_TE7hHUjt8VsTtPm8z6ku4wf8XFjJLuNlPp1XhcbM0t855c12swvfXLUZ9aljbIpLXd8NKZwfCIeDXaK9PR-vRRf3r39fHWd33x8_-HqzU3uKoSNZ4kWVQ1VJcvK9QPKRqquJS0JcQANjdYwdB3UylnotaamdQM1trTgSicvxYtTXv7-j0RxM7OPjqbJLrSmaLAqQdZVg_L_qGpbVIqVMlqeUBfWGAMN5hD8bMPRIJi9AGY0ewHMXgADaNgvBz2_z5-6mfo_Ib-NM_DqBBAL-ekpmOg8LezPBzZv-tX_O__rv8Ld5Bfv7PSdjhTHNYWFVRs0sTRgPu0tsHcAKuDBGn4B9P2sWA</recordid><startdate>20140301</startdate><enddate>20140301</enddate><creator>Wang, Qin</creator><creator>Li, Huayin</creator><creator>Zhou, Jian</creator><creator>Zhong, Ming</creator><creator>Zhu, Duming</creator><creator>Feng, Nana</creator><creator>Liu, Fanglei</creator><creator>Bai, Chunxue</creator><creator>Song, Yuanlin</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QL</scope><scope>C1K</scope></search><sort><creationdate>20140301</creationdate><title>PcrV antibody protects multi-drug resistant Pseudomonas aeruginosa induced acute lung injury</title><author>Wang, Qin ; Li, Huayin ; Zhou, Jian ; Zhong, Ming ; Zhu, Duming ; Feng, Nana ; Liu, Fanglei ; Bai, Chunxue ; Song, Yuanlin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c510t-c531a146055325cdf13734b9e83e11f0807880fbb064ca0d88e79cfe7a2a0c2c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Acute Lung Injury - drug therapy</topic><topic>Acute Lung Injury - etiology</topic><topic>Acute Lung Injury - pathology</topic><topic>Acute Lung Injury - therapy</topic><topic>ADP Ribose Transferases - metabolism</topic><topic>Animals</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Antibodies, Bacterial - therapeutic use</topic><topic>Antigens, Bacterial - immunology</topic><topic>Bacterial Proteins - metabolism</topic><topic>Bacterial Secretion Systems - physiology</topic><topic>Bacterial Toxins - immunology</topic><topic>Bacterial Toxins - metabolism</topic><topic>Ceftazidime - therapeutic use</topic><topic>Cytokines - blood</topic><topic>Drug Resistance, Multiple, Bacterial</topic><topic>Gene Expression</topic><topic>Immunization, Passive</topic><topic>Lung - drug effects</topic><topic>Lung - immunology</topic><topic>Lung - pathology</topic><topic>Mab166</topic><topic>Medical Education</topic><topic>Mice</topic><topic>Mice, Inbred BALB C</topic><topic>Multi-drug resistance</topic><topic>Neutrophils - immunology</topic><topic>PcrV</topic><topic>Pore Forming Cytotoxic Proteins - immunology</topic><topic>Pseudomonas aeruginosa</topic><topic>Pseudomonas aeruginosa - drug effects</topic><topic>Pseudomonas aeruginosa - pathogenicity</topic><topic>Pseudomonas Infections - complications</topic><topic>Pseudomonas Infections - drug therapy</topic><topic>Pseudomonas Infections - pathology</topic><topic>Pseudomonas Infections - therapy</topic><topic>Pulmonary/Respiratory</topic><topic>Species Specificity</topic><topic>Survival Analysis</topic><topic>Type III secretion system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Qin</creatorcontrib><creatorcontrib>Li, Huayin</creatorcontrib><creatorcontrib>Zhou, Jian</creatorcontrib><creatorcontrib>Zhong, Ming</creatorcontrib><creatorcontrib>Zhu, Duming</creatorcontrib><creatorcontrib>Feng, Nana</creatorcontrib><creatorcontrib>Liu, Fanglei</creatorcontrib><creatorcontrib>Bai, Chunxue</creatorcontrib><creatorcontrib>Song, Yuanlin</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Respiratory physiology & neurobiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Qin</au><au>Li, Huayin</au><au>Zhou, Jian</au><au>Zhong, Ming</au><au>Zhu, Duming</au><au>Feng, Nana</au><au>Liu, Fanglei</au><au>Bai, Chunxue</au><au>Song, Yuanlin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>PcrV antibody protects multi-drug resistant Pseudomonas aeruginosa induced acute lung injury</atitle><jtitle>Respiratory physiology & neurobiology</jtitle><addtitle>Respir Physiol Neurobiol</addtitle><date>2014-03-01</date><risdate>2014</risdate><volume>193</volume><spage>21</spage><epage>28</epage><pages>21-28</pages><issn>1569-9048</issn><eissn>1878-1519</eissn><abstract>Highlights • We analyzed the expression level of TTSS in clinically isolated multi-drug resistant Pseudomonas aeruginsoa strains and compared it with susceptible strains. • We investigated the effect of PcrV antibody on multi-drug resistant Pseudomonas aeruginosa induced acute lung injury. • The TTSS is comparatively conservative without correlation with antimicrobial resistance. • PcrV antibody could protect multi-drug resistant Pseudomonas aeruginosa induced acute lung injury.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>24418353</pmid><doi>10.1016/j.resp.2014.01.001</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1569-9048 |
| ispartof | Respiratory physiology & neurobiology, 2014-03, Vol.193, p.21-28 |
| issn | 1569-9048 1878-1519 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1520365713 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Acute Lung Injury - drug therapy Acute Lung Injury - etiology Acute Lung Injury - pathology Acute Lung Injury - therapy ADP Ribose Transferases - metabolism Animals Anti-Bacterial Agents - therapeutic use Antibodies, Bacterial - therapeutic use Antigens, Bacterial - immunology Bacterial Proteins - metabolism Bacterial Secretion Systems - physiology Bacterial Toxins - immunology Bacterial Toxins - metabolism Ceftazidime - therapeutic use Cytokines - blood Drug Resistance, Multiple, Bacterial Gene Expression Immunization, Passive Lung - drug effects Lung - immunology Lung - pathology Mab166 Medical Education Mice Mice, Inbred BALB C Multi-drug resistance Neutrophils - immunology PcrV Pore Forming Cytotoxic Proteins - immunology Pseudomonas aeruginosa Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - pathogenicity Pseudomonas Infections - complications Pseudomonas Infections - drug therapy Pseudomonas Infections - pathology Pseudomonas Infections - therapy Pulmonary/Respiratory Species Specificity Survival Analysis Type III secretion system |
| title | PcrV antibody protects multi-drug resistant Pseudomonas aeruginosa induced acute lung injury |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-07T19%3A58%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=PcrV%20antibody%20protects%20multi-drug%20resistant%20Pseudomonas%20aeruginosa%20induced%20acute%20lung%20injury&rft.jtitle=Respiratory%20physiology%20&%20neurobiology&rft.au=Wang,%20Qin&rft.date=2014-03-01&rft.volume=193&rft.spage=21&rft.epage=28&rft.pages=21-28&rft.issn=1569-9048&rft.eissn=1878-1519&rft_id=info:doi/10.1016/j.resp.2014.01.001&rft_dat=%3Cproquest_cross%3E1499144014%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1499144014&rft_id=info:pmid/24418353&rft_els_id=S1569904814000020&rfr_iscdi=true |