Neuronal and cardiovascular responses to ANF microinjected into the solitary nucleus

Neuronal and cardiovascular responses to ANF microinjected into the solitary nucleus

The effect on single-unit activity, arterial pressure, and heart rate of a microinjection of atrial natriuretic factor (ANF) into 78 histologically verified sites in the nucleus tractus solitarii (NTS) was investigated in rats. When injections of ANF caused either no effect or inhibition of single-u...

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Veröffentlicht in:American Journal of Physiology: Cell Physiology 1989-01, Vol.256 (2), p.R577-R582
Hauptverfasser: Ermirio, R, Ruggeri, P, Cogo, CE, Molinari, C, Calaresu, FR
Format: Artikel
Sprache:eng
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Zusammenfassung:The effect on single-unit activity, arterial pressure, and heart rate of a microinjection of atrial natriuretic factor (ANF) into 78 histologically verified sites in the nucleus tractus solitarii (NTS) was investigated in rats. When injections of ANF caused either no effect or inhibition of single-unit activity, no changes in either MAP or HR were observed. The results support the hypothesis that ANF plays a role in the chemical transmission of baroreceptor information within the NTS.
ISSN:0363-6143