Sitagliptin-induced bilateral Achilles tendinitis

Sitagliptin (Januvia) is a widely used oral dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of diabetes. Studies suggest that the drug is well-tolerated and no musculoskeletal side effects have been reported [1]. A 56-year-old female developed bilateral Achilles tendinitis 4 months after...

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Veröffentlicht in:	Rheumatology (Oxford, England) England), 2014-04, Vol.53 (4), p.630-630
Hauptverfasser:	Bussey, Melissa R, Emanuele, Mary Ann, Lomasney, Laurie M, Tehrani, Rodney
Format:	Artikel
Sprache:	eng
Schlagworte:	Achilles Tendon - pathology Diabetes Mellitus - drug therapy Female Humans Hypoglycemic Agents - adverse effects Magnetic Resonance Imaging Middle Aged Pyrazines - adverse effects Sitagliptin Phosphate Tendinopathy - chemically induced Tendinopathy - pathology Triazoles - adverse effects
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Zusammenfassung:	Sitagliptin (Januvia) is a widely used oral dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of diabetes. Studies suggest that the drug is well-tolerated and no musculoskeletal side effects have been reported [1]. A 56-year-old female developed bilateral Achilles tendinitis 4 months after restarting sitagliptin. There was no trauma to the Achilles tendons, but she had recently started a low-impact exercise programme; she stopped exercising with no relief.
ISSN:	1462-0324 1462-0332
DOI:	10.1093/rheumatology/ket395