Hepatitis B vaccination of adolescents: Significance of non-protective antibodies
Highlights • Anti-HBs antibodies were studied in HBV vaccinated adolescents. • Low rate of non-protected subjects were found as more than ten year follow-up. • Significance of 2 IU/L predicts values >10 IU/L after booster vaccination. • A new limit at 2 IU/L is proposed.
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| Veröffentlicht in: | Vaccine 2013-12, Vol.32 (1), p.62-68 |
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| container_end_page | 68 |
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| container_issue | 1 |
| container_start_page | 62 |
| container_title | Vaccine |
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| creator | Chiara, Federica Bartolucci, Giovanni Battista Cattai, Margherita Piazza, Anna Nicolli, Annamaria Buja, Alessandra Trevisan, Andrea |
| description | Highlights • Anti-HBs antibodies were studied in HBV vaccinated adolescents. • Low rate of non-protected subjects were found as more than ten year follow-up. • Significance of 2 IU/L predicts values >10 IU/L after booster vaccination. • A new limit at 2 IU/L is proposed. |
| doi_str_mv | 10.1016/j.vaccine.2013.10.074 |
| format | Article |
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Psychology ; Hepatitis ; Hepatitis B ; Hepatitis B - immunology ; Hepatitis B - prevention & control ; Hepatitis B Vaccines - immunology ; Hepatitis B virus ; Hepatitis B virus - immunology ; Human viral diseases ; Humans ; immune response ; Immunization ; Immunization, Secondary ; Infectious diseases ; Male ; Medical sciences ; Microbiology ; patients ; Persistence of antibodies ; probability ; Protective antibodies ; ROC Curve ; secondary immunization ; students ; Teenagers ; Vaccination ; Vaccines ; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) ; Viral diseases ; Viral hepatitis ; Young Adult</subject><ispartof>Vaccine, 2013-12, Vol.32 (1), p.62-68</ispartof><rights>Elsevier Ltd</rights><rights>2013 Elsevier Ltd</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2013 Elsevier Ltd. All rights reserved.</rights><rights>Copyright Elsevier Limited Dec 17, 2013</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c535t-1cacc3aaae694071e35b1d31e59774296170afc179964de15f658980efbd0113</citedby><cites>FETCH-LOGICAL-c535t-1cacc3aaae694071e35b1d31e59774296170afc179964de15f658980efbd0113</cites><orcidid>0000-0003-2396-3080 ; 0000-0003-2216-3807</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1551987556?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=28264664$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24188755$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chiara, Federica</creatorcontrib><creatorcontrib>Bartolucci, Giovanni Battista</creatorcontrib><creatorcontrib>Cattai, Margherita</creatorcontrib><creatorcontrib>Piazza, Anna</creatorcontrib><creatorcontrib>Nicolli, Annamaria</creatorcontrib><creatorcontrib>Buja, Alessandra</creatorcontrib><creatorcontrib>Trevisan, Andrea</creatorcontrib><title>Hepatitis B vaccination of adolescents: Significance of non-protective antibodies</title><title>Vaccine</title><addtitle>Vaccine</addtitle><description>Highlights • Anti-HBs antibodies were studied in HBV vaccinated adolescents. • Low rate of non-protected subjects were found as more than ten year follow-up. • Significance of <10 IU/L antibodies was evaluated. • Anti-HBs antibody level >2 IU/L predicts values >10 IU/L after booster vaccination. • A new limit at 2 IU/L is proposed.</description><subject>Adolescent</subject><subject>adolescents</subject><subject>Adult</subject><subject>adults</subject><subject>Allergy and Immunology</subject><subject>Anti-HBs</subject><subject>antibodies</subject><subject>Antibodies, Viral - blood</subject><subject>Antibodies, Viral - immunology</subject><subject>Antigens</subject><subject>Applied microbiology</subject><subject>Biological and medical sciences</subject><subject>Booster vaccination</subject><subject>Child</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Fundamental and applied biological sciences. 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Academic</collection><jtitle>Vaccine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chiara, Federica</au><au>Bartolucci, Giovanni Battista</au><au>Cattai, Margherita</au><au>Piazza, Anna</au><au>Nicolli, Annamaria</au><au>Buja, Alessandra</au><au>Trevisan, Andrea</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hepatitis B vaccination of adolescents: Significance of non-protective antibodies</atitle><jtitle>Vaccine</jtitle><addtitle>Vaccine</addtitle><date>2013-12-17</date><risdate>2013</risdate><volume>32</volume><issue>1</issue><spage>62</spage><epage>68</epage><pages>62-68</pages><issn>0264-410X</issn><eissn>1873-2518</eissn><coden>VACCDE</coden><abstract>Highlights • Anti-HBs antibodies were studied in HBV vaccinated adolescents. • Low rate of non-protected subjects were found as more than ten year follow-up. • Significance of <10 IU/L antibodies was evaluated. • Anti-HBs antibody level >2 IU/L predicts values >10 IU/L after booster vaccination. • A new limit at 2 IU/L is proposed.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>24188755</pmid><doi>10.1016/j.vaccine.2013.10.074</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0003-2396-3080</orcidid><orcidid>https://orcid.org/0000-0003-2216-3807</orcidid></addata></record> |
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| ispartof | Vaccine, 2013-12, Vol.32 (1), p.62-68 |
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| language | eng |
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| subjects | Adolescent adolescents Adult adults Allergy and Immunology Anti-HBs antibodies Antibodies, Viral - blood Antibodies, Viral - immunology Antigens Applied microbiology Biological and medical sciences Booster vaccination Child Female Follow-Up Studies Fundamental and applied biological sciences. Psychology Hepatitis Hepatitis B Hepatitis B - immunology Hepatitis B - prevention & control Hepatitis B Vaccines - immunology Hepatitis B virus Hepatitis B virus - immunology Human viral diseases Humans immune response Immunization Immunization, Secondary Infectious diseases Male Medical sciences Microbiology patients Persistence of antibodies probability Protective antibodies ROC Curve secondary immunization students Teenagers Vaccination Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Viral diseases Viral hepatitis Young Adult |
| title | Hepatitis B vaccination of adolescents: Significance of non-protective antibodies |
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