The Association between Adiposity, Mental Well-Being, and Quality of Life in Extreme Obesity: e92859

Objectives To explore the cross-sectional association between adiposity, mental well-being, and quality of life in extreme obese individuals entering a UK specialist weight management service prior to treatment commencement. Methods The sample comprised 263 extreme obese individuals who were referred to the service as a result of having a body mass index (BMI) greater than or equal to 40 kg/m2 or greater than or equal to 35 kg/m2 with a co-morbid health condition. In a retrospective analysis, routinely collected baseline clinical examination data and self-report questionnaires (Impact of Weight on Quality of Life: IWQOL-Lite, EQ5D-3L, and Hospital Anxiety and Depression Scale: HADS) were analysed to examine the cross-sectional association between adiposity and quality of life. Results The sample was predominantly female (74.8%) with mean BMI 47.0 plus or minus 7.9 kg/m2. Increasing adiposity was significantly negatively associated with quality of life, with an increase of 1 BMI unit associated with decreases of 1.93 in physical function (95% CI -2.86 - -1.00, p