VEGF, CD105 and α-SMA immunoexpression study in lips squamous cell carcinomas and associated dysplastic lesions

This study analyzes the microvascular density (MVD) for CD105+ and α-SMA+ vessels and VEGF immunoexpression for 35 oral squamous cell carcinomas and for the associated dysplastic lesions of the lips. CD105+ MVD was superior in the advancing edge compared to the intratumoral area, no matter the analy...

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Veröffentlicht in:	Romanian journal of morphology and embryology 2014, Vol.55 (1), p.35-41
Hauptverfasser:	Marinescu, Iulia Roxana, Simionescu, Cristiana Eugenia, Stepan, Alex Emilian, Mărgăritescu, Claudiu, Cernea, Daniela, Georgescu, Corneliu Cristian, Bălăşoiu, Maria, Olimid, Daniel Alin
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Analysis of Variance Antigens, CD - metabolism Carcinoma, Squamous Cell - blood supply Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology Endoglin Female Humans Immunohistochemistry Lip Neoplasms - blood supply Lip Neoplasms - metabolism Lip Neoplasms - pathology Male Microvessels - metabolism Microvessels - pathology Middle Aged Receptors, Cell Surface - metabolism Vascular Endothelial Growth Factor A - metabolism
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Zusammenfassung:	This study analyzes the microvascular density (MVD) for CD105+ and α-SMA+ vessels and VEGF immunoexpression for 35 oral squamous cell carcinomas and for the associated dysplastic lesions of the lips. CD105+ MVD was superior in the advancing edge compared to the intratumoral area, no matter the analyzed clinico-pathological parameters (gender, age, differentiation degree, tumor stage) (p
ISSN:	1220-0522