Differential Expression of Endothelium-specific Antigen PAL-E in Vasculature of Brain Tumors and Preexistent Brain Capillaries

Differential Expression of Endothelium-specific Antigen PAL-E in Vasculature of Brain Tumors and Preexistent Brain Capillaries

In the brain, blood vessels are lined by uniquely differentiated endothelium forming a barrier of selective permeability to a wide range of solutes, the blood-brain barrier (BBB). The authors investigated the expression of the antigen recognized by the monoclonal antibody PAL-E on endothelium in the...

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Veröffentlicht in:Annals of the New York Academy of Sciences 1988-06, Vol.529 (1), p.111-114
Hauptverfasser: SCHLINGEMANN, R. O., BOTS, G. Th. A. M., VAN DUINEN, S. G., RUITER, D. J.
Format: Artikel
Sprache:eng
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Zusammenfassung:In the brain, blood vessels are lined by uniquely differentiated endothelium forming a barrier of selective permeability to a wide range of solutes, the blood-brain barrier (BBB). The authors investigated the expression of the antigen recognized by the monoclonal antibody PAL-E on endothelium in the CNS. This antibody recognizes an endothelium-specific molecule of undefined molecular weight and function, which is associated with endothelial vesicles.
ISSN:0077-8923
1749-6632
DOI:10.1111/j.1749-6632.1988.tb51434.x