Semiquinone derivative isolated from Bacillus sp. INM-1 protects cellular antioxidant enzymes from γ-radiation-induced renal toxicity

This study was focused to evaluate protection of indigenous antioxidant system of mice against gamma radiation-induced oxidative stress using a semiquinone (SQGD)-rich fraction isolated from Bacillus sp. INM-1. Male C57bl/6 mice were administered SQGD (50 mg/kgb.w.i.p.) 2 h before irradiation (10 Gy...

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Veröffentlicht in:	Molecular and cellular biochemistry 2013-07, Vol.379 (1-2), p.19-27
Hauptverfasser:	Mishra, S., Reddy, D. S. K., Jamwal, V. S., Bansal, D. D., Patel, D. D., Malhotra, P., Gupta, A. K., Singh, P. K., Jawed, S., Kumar, Raj
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants Bacillus Bacillus - chemistry Benzoquinones - pharmacology Benzoquinones - therapeutic use Biochemistry Biomedical and Life Sciences Cardiology Catalase - metabolism Free Radical Scavengers - metabolism Gamma rays Glutathione - metabolism Glutathione transferase Glutathione Transferase - metabolism Kidney - drug effects Kidney - enzymology Kidney - radiation effects Life Sciences Male Medical Biochemistry Mice Mice, Inbred C57BL Nuclear radiation Oncology Oxidative Stress Quinone Radiation Injuries, Experimental - enzymology Radiation Injuries, Experimental - prevention & control Radiation-Protective Agents - pharmacology Radiation-Protective Agents - therapeutic use Superoxide Superoxide Dismutase - metabolism
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