Pathologically Confirmed Malignant Syphilis Using Immunohistochemical Staining: Report of 3 Cases and Review of the Literature

Malignant syphilis is a rare ulcerative variety. In the classical description of the disease, the absence of spirochetes in tissue samples was considered as a diagnostic criterion. We report 3 cases of malignant syphilis; in all of them, spirochetes were identified in cutaneous biopsy samples using...

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Veröffentlicht in:	Sexually transmitted diseases 2014-02, Vol.41 (2), p.94-97
Hauptverfasser:	Cid, Paola Maldonado, Cudós, Elena Sendagorta, Vargas, Francisco X. Zamora, Merino, María José Beato, Pinto, Pedro Herranz
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS-Related Opportunistic Infections - drug therapy AIDS-Related Opportunistic Infections - immunology AIDS-Related Opportunistic Infections - pathology Anti-Bacterial Agents - administration & dosage Biopsy Case Report CD4 Lymphocyte Count Humans Immunohistochemistry Injections, Intramuscular Male Malignant Penicillin G Benzathine - administration & dosage Severity of Illness Index Syphilis Syphilis, Cutaneous - drug therapy Syphilis, Cutaneous - immunology Syphilis, Cutaneous - pathology Tissues Treatment Outcome Treponema pallidum - isolation & purification Viral Load
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Zusammenfassung:	Malignant syphilis is a rare ulcerative variety. In the classical description of the disease, the absence of spirochetes in tissue samples was considered as a diagnostic criterion. We report 3 cases of malignant syphilis; in all of them, spirochetes were identified in cutaneous biopsy samples using immunohistochemical staining.
ISSN:	0148-5717 1537-4521
DOI:	10.1097/OLQ.0000000000000084