AIDS dementia complex and primary HIV brain infection

Infection with human immunodeficiency virus type 1 (HIV-1) can lead to a variety of central nervous system (CNS) complications, either indirectly as a result of opportunistic infections, opportunistic neoplasia and systemic organ failure, or, more directly, as a result of infection of the brain by t...

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Veröffentlicht in:	Journal of neuroimmunology 1988-12, Vol.20 (2), p.133-140
Hauptverfasser:	Brew, B.J., Rosenblum, M., Price, R.W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immunodeficiency syndrome Acquired Immunodeficiency Syndrome - complications Acquired Immunodeficiency Syndrome - drug therapy Acquired Immunodeficiency Syndrome - microbiology Brain Diseases - etiology Central nervous system complication Central Nervous System Diseases - etiology Dementia Dementia - complications Dementia - pathology Human immunodeficiency virus human immunodeficiency virus 1 Humans Meningitis, Aseptic - etiology Syndrome Zidovudine - adverse effects Zidovudine - therapeutic use
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Beschreibung
Zusammenfassung:	Infection with human immunodeficiency virus type 1 (HIV-1) can lead to a variety of central nervous system (CNS) complications, either indirectly as a result of opportunistic infections, opportunistic neoplasia and systemic organ failure, or, more directly, as a result of infection of the brain by this retrovirus. This review focuses on the conditions known or suspected to relate to a direct effect of HIV-1 on the brain with particular attention to the AIDS dementia complex.
ISSN:	0165-5728 1872-8421
DOI:	10.1016/0165-5728(88)90144-0