Helicobacter pylori diagnostics and treatment: could a lack of universal consensus be the best consensus?

In the US, however, there was a difference between 7 and 10 days but no significant difference between 10 and 14 days of ther- apy. [...]one would try to achieve the highest cure rate in the greatest number of patients with a duration of treatment that was not excessive but certainly not too short....

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Veröffentlicht in:	Clinical chemistry (Baltimore, Md.) Md.), 2014-04, Vol.60 (4), p.589-594
Hauptverfasser:	Couturier, Marc Roger, Marshall, Barry J, Goodman, Karen J, Mégraud, Francis
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - therapeutic use Antibiotics Australia Breath Tests Conflicts of interest Drug Resistance, Bacterial Drug therapy Drug Therapy, Combination Enzyme-Linked Immunosorbent Assay Europe Family physicians Feces - microbiology Helicobacter Infections - diagnosis Helicobacter Infections - drug therapy Helicobacter Infections - microbiology Helicobacter pylori - drug effects Helicobacter pylori - isolation & purification Humans Infections North America Patients Practice Guidelines as Topic Proton Pump Inhibitors - therapeutic use Serologic Tests Ulcers Urea - analysis
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Zusammenfassung:	In the US, however, there was a difference between 7 and 10 days but no significant difference between 10 and 14 days of ther- apy. [...]one would try to achieve the highest cure rate in the greatest number of patients with a duration of treatment that was not excessive but certainly not too short. The rule of thumb is that the 4 antibacterials mentioned immediately above can be reused in different combinations, often with a PPI, to broadly suppress H. pylori.
ISSN:	0009-9147 1530-8561
DOI:	10.1373/clinchem.2012.201475