Redox proteomics and the dynamic molecular landscape of the aging brain

Highlights • Aging is the major risk factor for development of many neurodegenerative diseases. • Protein oxidation increases in the brain with age. • Oxidative modifications of proteins impair their function. • Elevation of oxidized/misfolded brain proteins occurs in aging and neurodegeneration. •...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Ageing research reviews 2014, Vol.13, p.75-89
Hauptverfasser:	Perluigi, Marzia, Swomley, Aaron M, Butterfield, D. Allan
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Aging - metabolism Aging - pathology Animals Biological and medical sciences Biomarkers - metabolism Brain - metabolism Brain - pathology Caloric Restriction Development. Metamorphosis. Moult. Ageing Dogs Environment. Living conditions Fundamental and applied biological sciences. Psychology General aspects Humans Internal Medicine Medical sciences Mice Models, Animal Nerve Degeneration Nerve Tissue Proteins - metabolism Neurodegenerative Diseases - metabolism Neurodegenerative Diseases - pathology Neurology Oxidation-Reduction Protein Processing, Post-Translational Proteomics - methods Public health. Hygiene Public health. Hygiene-occupational medicine Rats Time Factors Vertebrates: anatomy and physiology, studies on body, several organs or systems
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!