Sumatriptan/naproxen sodium for the acute treatment of probable migraine without aura: A randomized study
Objective Probable migraine is a common, disabling migraine subtype fulfilling all but one of the diagnostic criteria for migraine. This study was conducted to evaluate the efficacy and tolerability of sumatriptan/naproxen sodium for the acute treatment of probable migraine without aura. Methods Pat...
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Veröffentlicht in: | Cephalalgia 2014-04, Vol.34 (4), p.268-279 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Objective
Probable migraine is a common, disabling migraine subtype fulfilling all but one of the diagnostic criteria for migraine. This study was conducted to evaluate the efficacy and tolerability of sumatriptan/naproxen sodium for the acute treatment of probable migraine without aura.
Methods
Patients treated a headache of probable migraine without aura when pain was moderate or severe with sumatriptan/naproxen sodium (n = 222 intent-to-treat (ITT)) or placebo (n = 221 ITT/complete case analysisa) in this randomized, double-blind, parallel-group study.
Results
Sumatriptan/naproxen sodium was more effective than placebo with respect to the co-primary efficacy endpoints two-hour pain-free response (29% sumatriptan/naproxen sodium vs 11% placebo, p |
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ISSN: | 0333-1024 1468-2982 |
DOI: | 10.1177/0333102413508242 |