Genome-wide association studies of atopic dermatitis

Atopic dermatitis is a common inflammatory disease caused by a combination of genetic and environmental factors. Genome‐wide association study (GWAS) is a comprehensive and unbiased approach to identify the genetic components of human diseases and to discover the cellular pathways underlying them. G...

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Veröffentlicht in:	Journal of dermatology 2014-03, Vol.41 (3), p.213-220
Hauptverfasser:	Tamari, Mayumi, Hirota, Tomomitsu
Format:	Artikel
Sprache:	eng
Schlagworte:	atopic dermatitis Dermatitis, Atopic - genetics Genetic Variation Genome-Wide Association Study Humans immunochip analysis polymorphisms
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Atopic dermatitis is a common inflammatory disease caused by a combination of genetic and environmental factors. Genome‐wide association study (GWAS) is a comprehensive and unbiased approach to identify the genetic components of human diseases and to discover the cellular pathways underlying them. GWAS and recent immunochip analysis of atopic dermatitis have identified a total of 19 associated loci with a genome‐wide level of significance (P
ISSN:	0385-2407 1346-8138
DOI:	10.1111/1346-8138.12321