TMS, cortical excitability and epilepsy: The clinical impact

Highlights • Paired-pulse TMS is a useful method for measurement of cortical excitability. • It provided novel information on pathophysiology and drug response of epilepsy. • The practical value is limited due to excess inter-individual variability. • TMS refinements are likely to offer information...

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Veröffentlicht in:	Epilepsy research 2014-02, Vol.108 (2), p.153-161
Hauptverfasser:	Badawy, Radwa A.B, Strigaro, Gionata, Cantello, Roberto
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Clinical applications Cortical excitability Epilepsy Epilepsy - diagnosis Epilepsy - physiopathology Epilepsy - therapy Evoked Potentials, Motor - physiology Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Medical sciences Motor Cortex - physiopathology Nervous system (semeiology, syndromes) Neurology Paired pulse transcranial magnetic stimulation Transcranial Magnetic Stimulation - methods Transcranial Magnetic Stimulation - trends
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Beschreibung
Zusammenfassung:	Highlights • Paired-pulse TMS is a useful method for measurement of cortical excitability. • It provided novel information on pathophysiology and drug response of epilepsy. • The practical value is limited due to excess inter-individual variability. • TMS refinements are likely to offer information at individual level in the future.
ISSN:	0920-1211 1872-6844
DOI:	10.1016/j.eplepsyres.2013.11.014