Neonatal stroke: a review of the current evidence on epidemiology, pathogenesis, diagnostics and therapeutic options

Neonatal stroke, including perinatal arterial ischaemic stroke and cerebral sinovenous thrombosis, remains a serious problem in the neonate. This article reviews the current evidence on epidemiology, pathogenesis, diagnostics and therapeutic options. Conclusion Although our understanding of the unde...

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Veröffentlicht in:Acta Paediatrica 2014-04, Vol.103 (4), p.356-364
Hauptverfasser: van der Aa, NE, Benders, MJNL, Groenendaal, F, de Vries, LS
Format: Artikel
Sprache:eng
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Zusammenfassung:Neonatal stroke, including perinatal arterial ischaemic stroke and cerebral sinovenous thrombosis, remains a serious problem in the neonate. This article reviews the current evidence on epidemiology, pathogenesis, diagnostics and therapeutic options. Conclusion Although our understanding of the underlying mechanisms and possible risk factors has improved, little progress has been made towards therapeutic options. Considering the high incidence of neurological sequelae, the need for therapeutic options is high and should be the focus of future research.
ISSN:0803-5253
1651-2227
DOI:10.1111/apa.12555