Primary cutaneous amyloidosis of the glans penis. Two case reports and a review of the literature

Summary Background Primary cutaneous amyloidosis of the penis is a rare entity. Objectives We describe two cases of primary penile cutaneous amyloidosis presenting as localized lesions on the penis and not associated with systemic amyloidosis. Methods A comprehensive literature review of all publish...

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Veröffentlicht in:British journal of dermatology (1951) 2014-03, Vol.170 (3), p.730-734
Hauptverfasser: Merika, E.E., Darling, M.Ι., Craig, P., Paul, M., Francis, N., Lachmann, H., Porter, W., Bunker, C.B.
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container_end_page 734
container_issue 3
container_start_page 730
container_title British journal of dermatology (1951)
container_volume 170
creator Merika, E.E.
Darling, M.Ι.
Craig, P.
Paul, M.
Francis, N.
Lachmann, H.
Porter, W.
Bunker, C.B.
description Summary Background Primary cutaneous amyloidosis of the penis is a rare entity. Objectives We describe two cases of primary penile cutaneous amyloidosis presenting as localized lesions on the penis and not associated with systemic amyloidosis. Methods A comprehensive literature review of all published cases. Results The rarest form of cutaneous amyloidosis, nodular amyloidosis, is the most frequent presentation of penis‐limited cutaneous amyloid with a low incidence of systemic disease progression. Conclusions Although primary nodular amyloidosis is a rare entity it seems to be the most frequent presentation of penile‐limited cutaneous disease, with a low incidence of systemic involvement. What's already known about this topic? Primary cutaneous amyloidosis of the penis is a rare entity. Nodular cutaneous amyloid is associated with systemic disease and up to 10% cases with associated paraproteinaemia progress to systemic disease. What does this study add? True penile‐limited cutaneous amyloidosis is highly associated with nodular amyloidosis. Primary cutaneous penile amyloidosis has a low incidence of systemic progression.
doi_str_mv 10.1111/bjd.12682
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Two case reports and a review of the literature</title><source>Oxford University Press Journals All Titles (1996-Current)</source><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Merika, E.E. ; Darling, M.Ι. ; Craig, P. ; Paul, M. ; Francis, N. ; Lachmann, H. ; Porter, W. ; Bunker, C.B.</creator><creatorcontrib>Merika, E.E. ; Darling, M.Ι. ; Craig, P. ; Paul, M. ; Francis, N. ; Lachmann, H. ; Porter, W. ; Bunker, C.B.</creatorcontrib><description>Summary Background Primary cutaneous amyloidosis of the penis is a rare entity. Objectives We describe two cases of primary penile cutaneous amyloidosis presenting as localized lesions on the penis and not associated with systemic amyloidosis. Methods A comprehensive literature review of all published cases. Results The rarest form of cutaneous amyloidosis, nodular amyloidosis, is the most frequent presentation of penis‐limited cutaneous amyloid with a low incidence of systemic disease progression. Conclusions Although primary nodular amyloidosis is a rare entity it seems to be the most frequent presentation of penile‐limited cutaneous disease, with a low incidence of systemic involvement. What's already known about this topic? Primary cutaneous amyloidosis of the penis is a rare entity. Nodular cutaneous amyloid is associated with systemic disease and up to 10% cases with associated paraproteinaemia progress to systemic disease. What does this study add? True penile‐limited cutaneous amyloidosis is highly associated with nodular amyloidosis. Primary cutaneous penile amyloidosis has a low incidence of systemic progression.</description><identifier>ISSN: 0007-0963</identifier><identifier>EISSN: 1365-2133</identifier><identifier>DOI: 10.1111/bjd.12682</identifier><identifier>PMID: 24125073</identifier><identifier>CODEN: BJDEAZ</identifier><language>eng</language><publisher>Oxford: Blackwell Publishing Ltd</publisher><subject>Amyloidosis ; Amyloidosis, Familial - pathology ; Biological and medical sciences ; Dermatology ; Humans ; Male ; Medical sciences ; Metabolic diseases ; Middle Aged ; Other metabolic disorders ; Penile Diseases - pathology ; Skin Diseases, Genetic - pathology</subject><ispartof>British journal of dermatology (1951), 2014-03, Vol.170 (3), p.730-734</ispartof><rights>2013 British Association of Dermatologists</rights><rights>2015 INIST-CNRS</rights><rights>2013 British Association of Dermatologists.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3932-a30a5edc7744c564bf6ea42e2c3577909ee2bb8826991669dc7ac6e4a9a9f5c3</citedby><cites>FETCH-LOGICAL-c3932-a30a5edc7744c564bf6ea42e2c3577909ee2bb8826991669dc7ac6e4a9a9f5c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fbjd.12682$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fbjd.12682$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=28344504$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24125073$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Merika, E.E.</creatorcontrib><creatorcontrib>Darling, M.Ι.</creatorcontrib><creatorcontrib>Craig, P.</creatorcontrib><creatorcontrib>Paul, M.</creatorcontrib><creatorcontrib>Francis, N.</creatorcontrib><creatorcontrib>Lachmann, H.</creatorcontrib><creatorcontrib>Porter, W.</creatorcontrib><creatorcontrib>Bunker, C.B.</creatorcontrib><title>Primary cutaneous amyloidosis of the glans penis. Two case reports and a review of the literature</title><title>British journal of dermatology (1951)</title><addtitle>Br J Dermatol</addtitle><description>Summary Background Primary cutaneous amyloidosis of the penis is a rare entity. Objectives We describe two cases of primary penile cutaneous amyloidosis presenting as localized lesions on the penis and not associated with systemic amyloidosis. Methods A comprehensive literature review of all published cases. Results The rarest form of cutaneous amyloidosis, nodular amyloidosis, is the most frequent presentation of penis‐limited cutaneous amyloid with a low incidence of systemic disease progression. Conclusions Although primary nodular amyloidosis is a rare entity it seems to be the most frequent presentation of penile‐limited cutaneous disease, with a low incidence of systemic involvement. What's already known about this topic? Primary cutaneous amyloidosis of the penis is a rare entity. Nodular cutaneous amyloid is associated with systemic disease and up to 10% cases with associated paraproteinaemia progress to systemic disease. What does this study add? True penile‐limited cutaneous amyloidosis is highly associated with nodular amyloidosis. Primary cutaneous penile amyloidosis has a low incidence of systemic progression.</description><subject>Amyloidosis</subject><subject>Amyloidosis, Familial - pathology</subject><subject>Biological and medical sciences</subject><subject>Dermatology</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Metabolic diseases</subject><subject>Middle Aged</subject><subject>Other metabolic disorders</subject><subject>Penile Diseases - pathology</subject><subject>Skin Diseases, Genetic - pathology</subject><issn>0007-0963</issn><issn>1365-2133</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kE1v00AQhlcIREPhwB9Ae0GCg9P9dvZIWmipqoAgEsfVeD2GLY4ddu2G_HsWnLQn5jIa6XlnNA8hLzmb81xn1W0958IsxCMy49LoQnApH5MZY6wsmDXyhDxL6ZYxLplmT8mJUFxoVsoZgc8xbCDuqR8H6LAfE4XNvu1D3aeQaN_Q4QfS7y10iW6xC2lO17ueekhII277OORAV1PI013A3THRhgEjDGPE5-RJA23CF4d-StYf3q_Pr4qbT5cfz9_dFF5aKQqQDDTWviyV8tqoqjEISqDwUpelZRZRVNViIYy13BibSfAGFViwjfbylLyZ1m5j_2vENLhNSB7bdvrK8fwvt1xYltG3E-pjn1LExm0nCY4z91eoy0LdP6GZfXVYO1YbrO_Jo8EMvD4AkDy0TYTOh_TALaRSmqnMnU3cLrS4__9Ft7y-OJ4upkRIA_6-T0D86UwpS-2-rS7darn68nV5tXZW_gGHuZux</recordid><startdate>201403</startdate><enddate>201403</enddate><creator>Merika, E.E.</creator><creator>Darling, M.Ι.</creator><creator>Craig, P.</creator><creator>Paul, M.</creator><creator>Francis, N.</creator><creator>Lachmann, H.</creator><creator>Porter, W.</creator><creator>Bunker, C.B.</creator><general>Blackwell Publishing Ltd</general><general>Wiley-Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201403</creationdate><title>Primary cutaneous amyloidosis of the glans penis. Two case reports and a review of the literature</title><author>Merika, E.E. ; Darling, M.Ι. ; Craig, P. ; Paul, M. ; Francis, N. ; Lachmann, H. ; Porter, W. ; Bunker, C.B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3932-a30a5edc7744c564bf6ea42e2c3577909ee2bb8826991669dc7ac6e4a9a9f5c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Amyloidosis</topic><topic>Amyloidosis, Familial - pathology</topic><topic>Biological and medical sciences</topic><topic>Dermatology</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Metabolic diseases</topic><topic>Middle Aged</topic><topic>Other metabolic disorders</topic><topic>Penile Diseases - pathology</topic><topic>Skin Diseases, Genetic - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Merika, E.E.</creatorcontrib><creatorcontrib>Darling, M.Ι.</creatorcontrib><creatorcontrib>Craig, P.</creatorcontrib><creatorcontrib>Paul, M.</creatorcontrib><creatorcontrib>Francis, N.</creatorcontrib><creatorcontrib>Lachmann, H.</creatorcontrib><creatorcontrib>Porter, W.</creatorcontrib><creatorcontrib>Bunker, C.B.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of dermatology (1951)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Merika, E.E.</au><au>Darling, M.Ι.</au><au>Craig, P.</au><au>Paul, M.</au><au>Francis, N.</au><au>Lachmann, H.</au><au>Porter, W.</au><au>Bunker, C.B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary cutaneous amyloidosis of the glans penis. Two case reports and a review of the literature</atitle><jtitle>British journal of dermatology (1951)</jtitle><addtitle>Br J Dermatol</addtitle><date>2014-03</date><risdate>2014</risdate><volume>170</volume><issue>3</issue><spage>730</spage><epage>734</epage><pages>730-734</pages><issn>0007-0963</issn><eissn>1365-2133</eissn><coden>BJDEAZ</coden><abstract>Summary Background Primary cutaneous amyloidosis of the penis is a rare entity. Objectives We describe two cases of primary penile cutaneous amyloidosis presenting as localized lesions on the penis and not associated with systemic amyloidosis. Methods A comprehensive literature review of all published cases. Results The rarest form of cutaneous amyloidosis, nodular amyloidosis, is the most frequent presentation of penis‐limited cutaneous amyloid with a low incidence of systemic disease progression. Conclusions Although primary nodular amyloidosis is a rare entity it seems to be the most frequent presentation of penile‐limited cutaneous disease, with a low incidence of systemic involvement. What's already known about this topic? Primary cutaneous amyloidosis of the penis is a rare entity. Nodular cutaneous amyloid is associated with systemic disease and up to 10% cases with associated paraproteinaemia progress to systemic disease. What does this study add? True penile‐limited cutaneous amyloidosis is highly associated with nodular amyloidosis. Primary cutaneous penile amyloidosis has a low incidence of systemic progression.</abstract><cop>Oxford</cop><pub>Blackwell Publishing Ltd</pub><pmid>24125073</pmid><doi>10.1111/bjd.12682</doi><tpages>5</tpages></addata></record>
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source Oxford University Press Journals All Titles (1996-Current); MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Amyloidosis
Amyloidosis, Familial - pathology
Biological and medical sciences
Dermatology
Humans
Male
Medical sciences
Metabolic diseases
Middle Aged
Other metabolic disorders
Penile Diseases - pathology
Skin Diseases, Genetic - pathology
title Primary cutaneous amyloidosis of the glans penis. Two case reports and a review of the literature
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