Role of capsule endoscopy Pillcam COLON 2 in patients with known or suspected Crohn’s disease who refused colonoscopy or underwent incomplete colonoscopic exam: a case series

Background Almost 70–80 % of patients with Crohn’s disease and virtually all patients with ulcerative colitis have colorectal mucosa involvement. Colon capsule endoscopy is an interesting option for patients unable or unwilling to undergo colonoscopy. We report our experience with the second-generation colon capsule PillCam ® COLON 2 in the detection of significant lesions in patients with known or suspected Crohn’s disease, who refused colonoscopy or underwent incomplete colonoscopic exam. Methods We have retrospectively reviewed the results of capsule endoscopy in 6 patients who refused colonoscopy ( n = 3) or underwent incomplete colonoscopic exam ( n = 3) between March 2011 and October 2012. In all patients, a CT scan was obtained before capsule endoscopy to rule out significant stenosis. Results In our series of 6 patients, 4 had both small bowel and colonic involvement. The use of the PillCam ® COLON 2 capsule allowed a thorough examination and evaluation of the mucosal lesions with high acceptability, the method being perceived as noninvasive by the patients. No adverse events related to the capsule or bowel preparation were recorded. Conclusion In this patient population, PillCam ® COLON 2 capsule endoscopy was safe. The capsule findings had an important impact on treatment decisions and patient management.