Serum vitamin D levels in children with recurrent otitis media

The aims of this study were to evaluate serum vitamin D levels in cases of recurrent otitis media and investigate the effect of vitamin D therapy on the risk of re-occurrence of the disease. This prospective study was performed by comparing serum vitamin D levels in children with recurrent otitis me...

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Veröffentlicht in:European archives of oto-rhino-laryngology 2014-04, Vol.271 (4), p.689-693
Hauptverfasser: Cayir, Atilla, Turan, Mehmet Ibrahim, Ozkan, Ozalkan, Cayir, Yasemin, Kaya, Avni, Davutoglu, Salih, Ozkan, Behzat
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Sprache:eng
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Zusammenfassung:The aims of this study were to evaluate serum vitamin D levels in cases of recurrent otitis media and investigate the effect of vitamin D therapy on the risk of re-occurrence of the disease. This prospective study was performed by comparing serum vitamin D levels in children with recurrent otitis media and healthy children. Eighty-four children between 1 and 5 years of age and diagnosed with recurrent otitis media were enrolled as the study group. One hundred-and-eight healthy children with similar demographic characteristics were enrolled as the control group. Patients were divided into groups according to their serum 25(OH) vitamin D levels. In patients with low initial serum vitamin D levels, vitamin D therapy was administered in addition to conventional treatment for otitis media. Mean serum 25(OH) vitamin D level in the study group was 11.4 ± 9.8 ng/mL Serum 25(OH) vitamin D levels were below 20 ng/mL in 69 % ( n  = 58) of cases in this group. In the control group, mean serum 25(OH) vitamin D level was 29.2 ± 13.9 ng/mL and was below 20 ng/mL in 30 % ( n  = 32) of cases. Comparison of serum 25(OH) vitamin D levels and PTH in the study and control groups revealed a statistically significant difference ( p  
ISSN:0937-4477
1434-4726
DOI:10.1007/s00405-013-2455-7