Pediatric misophonia with comorbid obsessive–compulsive spectrum disorders

Abstract Objective Misophonia is a potentially debilitating condition characterized by increased sensitivity to specific sounds, which cause subsequent behavioral and emotional responses. The nature, clinical phenomenology and etiology of misophonia remain unclear, and misophonic clinical presentations are not currently accounted for by existing psychiatric or audiological disorders. Method We present a case of pediatric misophonia in the context of comorbid obsessive–compulsive disorder and Tourette's syndrome. Results Given the interrelationships among obsessive–compulsive spectrum disorders and misophonia, these disorders may share underlying pathophysiology, particularly within the dopaminergic and serotonergic neural systems. Clinical (i.e., treatment) and theoretical implications are discussed.