In vitro susceptibility of Conidiobolus lamprauges recovered from sheep to antifungal agents

Data regarding the susceptibility of Conidiobolus lamprauges is limited and there is no consensus about the optimal treatment for infections caused by Conidiobolus spp. In this context, the objective of this study was to evaluate the in vitro susceptibility of six C. lamprauges strains isolated from...

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Veröffentlicht in:	Veterinary microbiology 2013-10, Vol.166 (3-4), p.690-693
Hauptverfasser:	Tondolo, Juliana Simoni Moraes, Loreto, Érico Silva de, Dutra, Valéria, Nakazato, Luciano, Paula, Daphine Ariadne Jesus de, Zanette, Régis Adriel, Alves, Sydney Hartz, Santurio, Janio Morais
Format:	Artikel
Sprache:	eng
Schlagworte:	amphotericin B Animals Antifungal Agents - pharmacology Conidiobolomycosis Conidiobolus Conidiobolus - drug effects Conidiobolus - genetics Conidiobolus - isolation & purification fluconazole flucytosine itraconazole ketoconazole Microbial Sensitivity Tests Sheep Sheep Diseases - drug therapy Sheep Diseases - microbiology Susceptibility testing Terbinafine Zygomycosis - drug therapy Zygomycosis - microbiology Zygomycosis - veterinary
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Zusammenfassung:	Data regarding the susceptibility of Conidiobolus lamprauges is limited and there is no consensus about the optimal treatment for infections caused by Conidiobolus spp. In this context, the objective of this study was to evaluate the in vitro susceptibility of six C. lamprauges strains isolated from sheep conidiobolomycosis to amphotericin B, ketoconazole, fluconazole, itraconazole, posaconazole, voriconazole, anidulafungin, caspofungin, micafungin, flucytosine, and terbinafine using the CLSI M38-A2 microdilution technique. Terbinafine was the most active (MIC range
ISSN:	0378-1135 1873-2542
DOI:	10.1016/j.vetmic.2013.07.024