Comparison of two commercial vaccines against visceral leishmaniasis in dogs from endemic areas: IgG, and subclasses, parasitism, and parasite transmission by xenodiagnosis
Highlights • Two commercial vaccines against canine visceral leishmaniasis were compared. • The outcome of vaccination of pet dogs was evaluated in endemic natural conditions. • A controlled prospective clinical approach was used to monitor the vaccinated dogs. • Post-vaccinal xenodiagnosis, serolog...
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| Veröffentlicht in: | Vaccine 2014-03, Vol.32 (11), p.1287-1295 |
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| creator | Fernandes, Consuelo Barreto Junior, Jairo Torres Magalhães de Jesus, Clauceane Souza, Bárbara Maria Paraná da Silva Larangeira, Daniela Farias Fraga, Deborah Bittencourt Mothé Tavares Veras, Patricia Sampaio Barrouin-Melo, Stella Maria |
| description | Highlights • Two commercial vaccines against canine visceral leishmaniasis were compared. • The outcome of vaccination of pet dogs was evaluated in endemic natural conditions. • A controlled prospective clinical approach was used to monitor the vaccinated dogs. • Post-vaccinal xenodiagnosis, serology, parasitology, and clinical data were similar. • Reactogenicity and IgG subclass profile resulted in main differences among vaccines. |
| doi_str_mv | 10.1016/j.vaccine.2013.12.046 |
| format | Article |
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Junior, Jairo Torres Magalhães ; de Jesus, Clauceane ; Souza, Bárbara Maria Paraná da Silva ; Larangeira, Daniela Farias ; Fraga, Deborah Bittencourt Mothé ; Tavares Veras, Patricia Sampaio ; Barrouin-Melo, Stella Maria</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c558t-562d74c7922e6b7ece09dd4ff10d46772f46de1f9f26acb5a634aaf97a07cec83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Allergy and Immunology</topic><topic>Animals</topic><topic>Antibodies, Protozoan - blood</topic><topic>Applied microbiology</topic><topic>Biological and medical sciences</topic><topic>Brazil</topic><topic>Canine immunization</topic><topic>Dog Diseases - parasitology</topic><topic>Dog Diseases - prevention & control</topic><topic>Dogs</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. 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| ispartof | Vaccine, 2014-03, Vol.32 (11), p.1287-1295 |
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| language | eng |
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| subjects | Allergy and Immunology Animals Antibodies, Protozoan - blood Applied microbiology Biological and medical sciences Brazil Canine immunization Dog Diseases - parasitology Dog Diseases - prevention & control Dogs Female Fundamental and applied biological sciences. Psychology Human protozoal diseases Immunity, Humoral Immunoglobulin G - blood Infections Infectious diseases Leishmania infantum Leishmaniasis Vaccines - adverse effects Leishmaniasis Vaccines - therapeutic use Leishmaniasis, Visceral - diagnosis Leishmaniasis, Visceral - prevention & control Leishmaniasis, Visceral - veterinary Leishmune® and Leish-Tec Leshmaniasis Lutzomyia longipalpis Male Medical sciences Microbiology Parasites Parasitic diseases Parasitism Prospective Studies Protozoal diseases Reactogenicity Side effects Vaccination - veterinary Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Vector-borne diseases Xenodiagnosis |
| title | Comparison of two commercial vaccines against visceral leishmaniasis in dogs from endemic areas: IgG, and subclasses, parasitism, and parasite transmission by xenodiagnosis |
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