Development of ‘leaky’ liposome triggered by radiation applicable to a drug reservoir and a simple radiation dosimeter

Radiation effects on permeability of liposomes with different lipid compositions and the content ratios were investigated using X-rays. Liposomes constituted from an unsaturated phosphatidylcholine (PC), a saturated PC, and cholesterol were selected. As a result, we found that a PC with bis-allylic...

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Veröffentlicht in:	Applied radiation and isotopes 2013-04, Vol.74, p.144-151
1. Verfasser:	Akamatsu, Ken
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug Delivery Systems Ionizing radiation Lipid peroxidation Liposome Liposomes - chemistry Liposomes - radiation effects Molecular Structure Permeability Permeability - radiation effects Phosphatidylcholines - chemistry Phosphatidylcholines - radiation effects Radiometry - instrumentation
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