Overdose of Drugs for Attention-Deficit Hyperactivity Disorder: Clinical Presentation, Mechanisms of Toxicity, and Management

The prevalence of attention-deficit hyperactivity disorder (ADHD) in the USA is estimated at approximately 4–9 % in children and 4 % in adults. It is estimated that prescriptions for ADHD medications are written for more than 2.7 million children per year. In 2010, US poison centers reported 17,000...

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Veröffentlicht in:	CNS drugs 2013-07, Vol.27 (7), p.531-543
Hauptverfasser:	Spiller, Henry A., Hays, Hannah L., Aleguas, Alfred
Format:	Artikel
Sprache:	eng
Schlagworte:	Attention Deficit Disorder with Hyperactivity - drug therapy Attention Deficit Disorder with Hyperactivity - epidemiology Attention deficit hyperactivity disorder Blood pressure Cardiac arrhythmia Central Nervous System Depressants - administration & dosage Central Nervous System Depressants - pharmacokinetics Central Nervous System Depressants - therapeutic use Central Nervous System Depressants - toxicity Central Nervous System Stimulants - administration & dosage Central Nervous System Stimulants - pharmacokinetics Central Nervous System Stimulants - therapeutic use Central Nervous System Stimulants - toxicity Dopamine Drug dosages Drug Overdose - diagnosis Drug Overdose - etiology Drug Overdose - therapy Drug therapy Drug-Related Side Effects and Adverse Reactions - diagnosis Drug-Related Side Effects and Adverse Reactions - etiology Drug-Related Side Effects and Adverse Reactions - therapy Humans Hypertension Medicine Medicine & Public Health Neurology Neurosciences Pharmacotherapy Plasma Poisons Psychiatry Psychopharmacology Review Article Serotonin Toxicity
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Zusammenfassung:	The prevalence of attention-deficit hyperactivity disorder (ADHD) in the USA is estimated at approximately 4–9 % in children and 4 % in adults. It is estimated that prescriptions for ADHD medications are written for more than 2.7 million children per year. In 2010, US poison centers reported 17,000 human exposures to ADHD medications, with 80 % occurring in children
ISSN:	1172-7047 1179-1934
DOI:	10.1007/s40263-013-0084-8